STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1289Similar to Mycobacterium tuberculosis CDC1551 ABC transporter, ATP-binding protein MT1519 SWALL:AAK45784 (EMBL:AE007021) (542 aa) fasta scores: E(): 2.2e-114, 70.95% id in 544 aa, and to Bacillus halodurans ABC transporter BH2025 SWALL:Q9KBA3 (EMBL:AP001514) (539 aa) fasta scores: E(): 6.5e-33, 32.07% id in 505 aa. (543 aa)    
Predicted Functional Partners:
DIP1288
Conserved hypothetical protein; Similar to Bacillus subtilis hypothetical YxlE SWALL:P94373 (EMBL:D83026) (62 aa) fasta scores: E(): 0.028, 31.03% id in 58 aa.
       0.730
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.700
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
   0.698
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.697
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.697
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.696
DIP1290
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.4 kDa protein Rv1466 or MTV007.13 SWALL:O53157 (EMBL:AL021184) (115 aa) fasta scores: E(): 6.7e-24, 67.3% id in 104 aa, and to Deinococcus radiodurans conserved hypothetical protein DR2165 SWALL:Q9RSF9 (EMBL:AE002050) (149 aa) fasta scores: E(): 1.1e-13, 43.59% id in 117 aa.
       0.690
DIP1291
Similar to Mycobacterium tuberculosis CDC1551 nitrogen fixation protein NifU-related protein MT1512 SWALL:AAK45776 (EMBL:AE007020) (162 aa) fasta scores: E(): 2.6e-35, 63.69% id in 146 aa, and to Bacillus subtilis NifU-like protein NifU SWALL:NIFU_BACSU (SWALL:O32163) (147 aa) fasta scores: E(): 3.7e-18, 44.21% id in 147 aa.
       0.690
csd
Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
       0.690
DIP1293
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCC22.04c SWALL:Q9XAD4 (EMBL:AL096839) (254 aa) fasta scores: E(): 4.3e-58, 70.4% id in 250 aa, and to Mycobacterium tuberculosis hypothetical 28.8 kDa protein Rv1463 or MTV007.10 SWALL:O53154 (EMBL:AL021184) (266 aa) fasta scores: E(): 8.8e-59, 70% id in 250 aa, and to Staphylococcus aureus (strain N315) SA0774 protein or SAV0842 SWALL:BAB57004 (EMBL:AP003131) (253 aa) fasta scores: E(): 1.7e-44, 58.63% id in 249 aa.
       0.690
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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