Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DIP1289Similar to Mycobacterium tuberculosis CDC1551 ABC transporter, ATP-binding protein MT1519 SWALL:AAK45784 (EMBL:AE007021) (542 aa) fasta scores: E(): 2.2e-114, 70.95% id in 544 aa, and to Bacillus halodurans ABC transporter BH2025 SWALL:Q9KBA3 (EMBL:AP001514) (539 aa) fasta scores: E(): 6.5e-33, 32.07% id in 505 aa. (543 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.742
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.737
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.734
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
   0.733
rpmD
Similar to Streptomyces coelicolor 50S ribosomal protein L30 RpmD or SCD31.45 SW:RL30_STRCO (P46789) (60 aa) fasta scores: E(): 2.1e-08, 53.57% id in 56 aa.
   
   0.732
rpmH
50S ribosomal protein L34; Similar to Mycobacterium paratuberculosis 50S ribosomal protein L34 RpmH SW:RL34_MYCPA (Q9L7L8) (47 aa) fasta scores: E(): 2.9e-15, 80.85% id in 47 aa, to Streptomyces bikiniensis 50S ribosomal protein L34 RpmH SW:RL34_STRBI (P25820) (45 aa) fasta scores: E(): 2.2e-13, 81.39% id in 43 aa, and to Escherichia coli 50S ribosomal protein L34 Rpmh or SsaF or RimA or B3703 or Z5194 or ECS4638 or STM3839 SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 1.1e-07, 59.52% id in 42 aa; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.729
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.725
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.725
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
   0.724
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.724
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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