STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1294Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 42.5 kDa protein Rv1462 or MT1509 or MTV007.09 SWALL:YE62_MYCTU (SWALL:O53153) (397 aa) fasta scores: E(): 7.7e-84, 56.05% id in 380 aa, and to Streptomyces coelicolor conserved hypothetical protein SCC22.06c SWALL:Q9XAD2 (EMBL:AL096839) (394 aa) fasta scores: E(): 6.1e-75, 52.86% id in 367 aa. (391 aa)    
Predicted Functional Partners:
DIP1293
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCC22.04c SWALL:Q9XAD4 (EMBL:AL096839) (254 aa) fasta scores: E(): 4.3e-58, 70.4% id in 250 aa, and to Mycobacterium tuberculosis hypothetical 28.8 kDa protein Rv1463 or MTV007.10 SWALL:O53154 (EMBL:AL021184) (266 aa) fasta scores: E(): 8.8e-59, 70% id in 250 aa, and to Staphylococcus aureus (strain N315) SA0774 protein or SAV0842 SWALL:BAB57004 (EMBL:AP003131) (253 aa) fasta scores: E(): 1.7e-44, 58.63% id in 249 aa.
 
 
 0.998
csd
Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 
 0.989
DIP1291
Similar to Mycobacterium tuberculosis CDC1551 nitrogen fixation protein NifU-related protein MT1512 SWALL:AAK45776 (EMBL:AE007020) (162 aa) fasta scores: E(): 2.6e-35, 63.69% id in 146 aa, and to Bacillus subtilis NifU-like protein NifU SWALL:NIFU_BACSU (SWALL:O32163) (147 aa) fasta scores: E(): 3.7e-18, 44.21% id in 147 aa.
 
  
 0.966
DIP1295
Similar to Streptomyces coelicolor conserved hypothetical protein SCC22.07c SWALL:Q9XAD1 (EMBL:AL096839) (473 aa) fasta scores: E(): 1.9e-154, 82.78% id in 459 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0778 or SAV0846 SWALL:Q99VF9 (EMBL:AP003131) (465 aa) fasta scores: E(): 1.7e-123, 65.14% id in 459 aa.
 
   
0.917
DIP1296
Putative DNA-binding protein; Similar to Mycobacterium tuberculosis hypothetical 29.2 kDa protein Rv1460 or MTV007.07 SWALL:O53151 (EMBL:AL021184) (278 aa) fasta scores: E(): 3.4e-38, 46.25% id in 240 aa, and to Streptomyces coelicolor putative DNA-binding protein scc22.08C SWALL:Q9XAD0 (EMBL:AL096839) (252 aa) fasta scores: E(): 9e-27, 42.35% id in 229 aa.
  
  
 0.905
DIP1290
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.4 kDa protein Rv1466 or MTV007.13 SWALL:O53157 (EMBL:AL021184) (115 aa) fasta scores: E(): 6.7e-24, 67.3% id in 104 aa, and to Deinococcus radiodurans conserved hypothetical protein DR2165 SWALL:Q9RSF9 (EMBL:AE002050) (149 aa) fasta scores: E(): 1.1e-13, 43.59% id in 117 aa.
 
   
 0.899
DIP0176
Similar to Mycobacterium leprae hypothetical protein ML0117 TR:Q9CD97 (EMBL:AL583917) (398 aa) fasta scores: E(): 8.1e-38, 35.73% id in 417 aa.
  
 
 0.782
ahpD
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
      
 0.705
DIP1289
Similar to Mycobacterium tuberculosis CDC1551 ABC transporter, ATP-binding protein MT1519 SWALL:AAK45784 (EMBL:AE007021) (542 aa) fasta scores: E(): 2.2e-114, 70.95% id in 544 aa, and to Bacillus halodurans ABC transporter BH2025 SWALL:Q9KBA3 (EMBL:AP001514) (539 aa) fasta scores: E(): 6.5e-33, 32.07% id in 505 aa.
       0.636
DIP0619
Putative diphtheria toxin repressor 2; Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or MT2784 or MTCY05A6.32 SW:IDER_MYCTU (Q50495) (230 aa) fasta scores: E(): 1.1e-10, 31.84% id in 201 aa and low similarity to Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.7e-08, 35.08% identity in 114 aa overlap.
     
 0.554
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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