STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1300Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1456c or MT1503 or MTV007.03C SWALL:AAK45767 (EMBL:AL021184) (311 aa) fasta scores: E(): 3.7e-43, 43.75% id in 304 aa, and to Streptomyces coelicolor putative integral membrane transport protein SCC22.12 SWALL:Q9XAC6 (EMBL:AL096839) (356 aa) fasta scores: E(): 6.9e-24, 33.01% id in 312 aa, and low similarity to Bacillus firmus cytochrome aa3 controlling protein ctaA SWALL:CTAA_BACFI (SWALL:Q04443) (297 aa) fasta scores: E(): 0.0021, 21.42% id in 266 aa. (312 aa)    
Predicted Functional Partners:
ctaB
Putative farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.998
DIP1299
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 27.4 kDa protein Rv1457c or MTV007.04c SWALL:O86349 (EMBL:AL021184) (261 aa) fasta scores: E(): 1.5e-31, 41.47% id in 258 aa, and to Mycobacterium smegmatis hypothetical 24.4 kDa protein SWALL:O87317 (EMBL:AF027770) (236 aa) fasta scores: E(): 1.1e-23, 37.55% id in 237 aa.
 
   
 0.892
DIP1684
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 29.8 kDa protein Rv2235 precursor or MT2294 or MTCY427.16 SW:YM35_MYCTU (Q10517) (271 aa) fasta scores: E(): 1.4e-34, 38.54% id in 275 aa.
 
 
 0.870
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
 
  
 0.844
qcrA
Ubiquinol-cytochrome C reductase iron-sulfur protein; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis; Belongs to the Rieske iron-sulfur protein family.
  
  
 0.767
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
 
   
 0.765
DIP1297
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 62.7 kDa protein Rv1459c or MT1506 or MTV007.06c SWALL:AAK45770 (EMBL:AL021184) (591 aa) fasta scores: E(): 2.6e-33, 36.63% id in 546 aa, and to Mycobacterium tuberculosis putative membrane protein Rv2174 or MT2230 or MTV021.07 SWALL:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.1e-18, 30.6% id in 464 aa, and low similarity to Rhizobium meliloti putative cytochrome C oxidase polypeptide I transmembrane protein CtaD or R00905 or SMC00010 SWALL:Q92RG9 (EMBL:AL591785) (562 aa) fasta scores: E(): 1.6, 22.9 [...]
     
 0.732
DIP1805
Putative membrane protein; Similar to Mycobacterium leprae hypothetical protein ML1998 SW:Y102_MYCLE (P53525) (659 aa) fasta scores: E(): 2e-44, 31.72% id in 665 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa) fasta scores: E(): 2.2e-44, 30.76% id in 650 aa.
 
   
 0.726
DIP1298
Similar to Mycobacterium tuberculosis ABC-transporter ATP-binding protein Rv1458c or MTV007.05c SWALL:O53149 (EMBL:AL021184) (313 aa) fasta scores: E(): 2e-48, 50.32% id in 304 aa, and to Streptomyces peucetius daunorubicin resistance ATP-binding protein DrrA SWALL:DRRA_STRPE (SWALL:P32010) (330 aa) fasta scores: E(): 1.5e-24, 34.09% id in 305 aa.
     
 0.714
ctaF
Putative membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
  
     0.678
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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