STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (700 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 0.999
pgi
Similar to Escherichia coli glucose-6-phosphate isomerase Pgi or B4025 or Z5623 or ECS5008 SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 2e-104, 52.71% id in 552 aa, and to Mycobacterium tuberculosis glucose-6-phosphate isomerase Pgi or Rv0946c or MT0972 or MTCY10D7.28 SW:G6PI_MYCTU (P77895) (553 aa) fasta scores: E(): 2.6e-133, 62.75% id in 545 aa.
  
 0.983
rpe
Similar to Mycobacterium tuberculosis ribulose-phosphate 3-epimerase Rpe or Rv1408 or MT1452 or MTCY21B4.25 SWALL:RPE_MYCTU (SWALL:P71676) (229 aa) fasta scores: E(): 2e-49, 58.63% id in 220 aa, and to Escherichia coli ribulose-phosphate 3-epimerase Rpe or Dod or B3386 or Z4739 or ECS4228 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 1.3e-30, 43.19% id in 213 aa.
 0.982
DIP0939
Similar to Streptomyces coelicolor conserved hypothetical protein SCK7.20c TR:Q9FBN2 (EMBL:AL391754) (343 aa) fasta scores: E(): 7.1e-79, 67.89% id in 327 aa, and to Escherichia coli protein GlpX or B3925 SW:GLPX_ECOLI (P28860) (336 aa) fasta scores: E(): 4.6e-39, 44.61% id in 325 aa.
   
 0.970
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.957
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.947
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
 0.942
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
  
 
 0.931
DIP1796
Putative ribose/galactose isomerase; Similar to Staphylococcus aureus galactose-6-phosphate isomerase subunit LacB SW:LACB_STAAU (P26592) (171 aa) fasta scores: E(): 2e-13, 36.53% id in 156 aa, and to Mycobacterium tuberculosis putative isomerase Rv2465c TR:AAK46840 (EMBL:AL021246) (159 aa) fasta scores: E(): 4.1e-45, 76.77% id in 155 aa.
  
 
 0.928
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.927
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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