STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pglPutative phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (238 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
DIP1305
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 37.7 kDa protein SCC22.20 SWALL:Q9XAB8 (EMBL:AL096839) (351 aa) fasta scores: E(): 1.5e-36, 41.82% id in 318 aa, and to Mycobacterium tuberculosis hypothetical 32.7 kDa protein OpcA or Rv1446c or MT1493 or MTCY493.08 SWALL:AAK45756 (EMBL:Z95844) (303 aa) fasta scores: E(): 9.5e-35, 39.3% id in 318 aa.
  
 0.979
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
 
 0.948
DIP0254
Putative transferase; Similar to Streptomyces coelicolor putative gluconokinase SCI52.21 TR:Q9AD88 (EMBL:AL590507) (175 aa) fasta scores: E(): 4.2e-33, 60.39% id in 154 aa, and to Escherichia coli thermosensitive gluconokinase IdnK or GntV or B4268 SW:IDNK_ECOLI (P39208) (187 aa) fasta scores: E(): 3e-20, 44.15% id in 154 aa.
   
 0.912
DIP0892
Similar to Streptomyces coelicolor putative glyceraldehyde-3-phosphate dehydrogenase SC4G1.06c TR:Q9FC43 (EMBL:AL391039) (481 aa) fasta scores: E(): 1.8e-99, 54.44% id in 472 aa and C-terminal region similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 GapA or Gap SW:G3P1_BACSU (P09124) (334 aa) fasta scores: E(): 6.7e-40, 41.39% id in 343 aa.
   
  
 0.879
gap
Similar to Corynebacterium glutamicum glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_CORGL (SWALL:Q01651) (336 aa) fasta scores: E(): 5.5e-99, 80% id in 330 aa, and to Streptomyces coelicolor glyceraldehyde 3-phosphate dehydrogenase Gap or SCC54.07c SWALL:G3P_STRCO (SWALL:Q9Z518) (336 aa) fasta scores: E(): 1.1e-84, 67.26% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.879
DIP0939
Similar to Streptomyces coelicolor conserved hypothetical protein SCK7.20c TR:Q9FBN2 (EMBL:AL391754) (343 aa) fasta scores: E(): 7.1e-79, 67.89% id in 327 aa, and to Escherichia coli protein GlpX or B3925 SW:GLPX_ECOLI (P28860) (336 aa) fasta scores: E(): 4.6e-39, 44.61% id in 325 aa.
     
 0.873
glk
Glucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa.
     
 0.870
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
      
 0.845
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 
 
 0.815
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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