STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Similar to Corynebacterium glutamicum phosphoglycerate kinase Pgk SWALL:PGK_CORGL (SWALL:Q01655) (403 aa) fasta scores: E(): 8.9e-111, 74.5% id in 404 aa, and to Bacillus subtilis phosphoglycerate kinase Pgk SWALL:PGK_BACSU (SWALL:P40924) (394 aa) fasta scores: E(): 1.4e-66, 51.47% id in 406 aa. (405 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
gap
Similar to Corynebacterium glutamicum glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_CORGL (SWALL:Q01651) (336 aa) fasta scores: E(): 5.5e-99, 80% id in 330 aa, and to Streptomyces coelicolor glyceraldehyde 3-phosphate dehydrogenase Gap or SCC54.07c SWALL:G3P_STRCO (SWALL:Q9Z518) (336 aa) fasta scores: E(): 1.1e-84, 67.26% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
DIP0892
Similar to Streptomyces coelicolor putative glyceraldehyde-3-phosphate dehydrogenase SC4G1.06c TR:Q9FC43 (EMBL:AL391039) (481 aa) fasta scores: E(): 1.8e-99, 54.44% id in 472 aa and C-terminal region similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 GapA or Gap SW:G3P1_BACSU (P09124) (334 aa) fasta scores: E(): 6.7e-40, 41.39% id in 343 aa.
 
 0.996
gpmA
Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.991
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.987
pgi
Similar to Escherichia coli glucose-6-phosphate isomerase Pgi or B4025 or Z5623 or ECS5008 SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 2e-104, 52.71% id in 552 aa, and to Mycobacterium tuberculosis glucose-6-phosphate isomerase Pgi or Rv0946c or MT0972 or MTCY10D7.28 SW:G6PI_MYCTU (P77895) (553 aa) fasta scores: E(): 2.6e-133, 62.75% id in 545 aa.
  
 
 0.951
pyk
Pyruvate kinase; Similar to Corynebacterium glutamicum pyruvate kinase Pyk SW:KPYK_CORGL (Q46078) (475 aa) fasta scores: E(): 1.3e-146, 83.36% id in 469 aa, and to Bacillus psychrophilus pyruvate kinase Pyk SW:KPYK_BACPY (P51182) (586 aa) fasta scores: E(): 6.9e-64, 41.45% id in 480 aa.
 
 
 0.944
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.940
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.860
rpe
Similar to Mycobacterium tuberculosis ribulose-phosphate 3-epimerase Rpe or Rv1408 or MT1452 or MTCY21B4.25 SWALL:RPE_MYCTU (SWALL:P71676) (229 aa) fasta scores: E(): 2e-49, 58.63% id in 220 aa, and to Escherichia coli ribulose-phosphate 3-epimerase Rpe or Dod or B3386 or Z4739 or ECS4228 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 1.3e-30, 43.19% id in 213 aa.
 
 
 0.787
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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