STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1312Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (323 aa)    
Predicted Functional Partners:
DIP1313
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.952
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
 
  
 0.920
uvrC
Putative excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.813
DIP1315
Putative membrane protein; Similar to Corynebacterium ammoniagenes RibX protein SWALL:O24754 (EMBL:AB003693) (184 aa) fasta scores: E(): 1.3e-34, 45.98% id in 187 aa, and to Mycobacterium leprae putative membrane protein ML0561 SWALL:Q9CCP2 (EMBL:AL583918) (156 aa) fasta scores: E(): 2.3e-15, 37.58% id in 141 aa.
       0.813
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
       0.643
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
       0.643
DIP0057
Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa.
  
  
 0.578
gap
Similar to Corynebacterium glutamicum glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_CORGL (SWALL:Q01651) (336 aa) fasta scores: E(): 5.5e-99, 80% id in 330 aa, and to Streptomyces coelicolor glyceraldehyde 3-phosphate dehydrogenase Gap or SCC54.07c SWALL:G3P_STRCO (SWALL:Q9Z518) (336 aa) fasta scores: E(): 1.1e-84, 67.26% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
     
 0.567
ribE
Similar to Actinobacillus pleuropneumoniae riboflavin synthase alpha chain RibE or RibB SWALL:RISA_ACTPL (SWALL:P50854) (215 aa) fasta scores: E(): 7.6e-32, 49% id in 200 aa, and to Mycobacterium tuberculosis riboflavin synthase alpha chain RibE or RibC or Rv1412 or MT1456 or MTCY21B4.29 SWALL:RISA_MYCTU (SWALL:P71680) (201 aa) fasta scores: E(): 8.6e-39, 58.29% id in 199 aa, and to Bacillus subtilis riboflavin synthase alpha chain RibE or RibB SWALL:RISA_BACSU (SWALL:P16440) (215 aa) fasta scores: E(): 1.2e-25, 43.06% id in 202 aa.
       0.554
ribD
Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.536
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.