| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIP1321 | def-2 | DIP1321 | DIP1323 | Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.783 |
| DIP1321 | fmt | DIP1321 | DIP1322 | Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.973 |
| DIP1321 | rplX | DIP1321 | DIP0487 | Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.724 |
| def-2 | DIP1321 | DIP1323 | DIP1321 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.783 |
| def-2 | fmt | DIP1323 | DIP1322 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.955 |
| def-2 | rplI | DIP1323 | DIP2289 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.793 |
| def-2 | rplT | DIP1323 | DIP1162 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.759 |
| def-2 | rplU | DIP1323 | DIP1781 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.798 |
| def-2 | rplX | DIP1323 | DIP0487 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.771 |
| def-2 | rplY | DIP1323 | DIP0901 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Putative 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.746 |
| def-2 | rpmA | DIP1323 | DIP1780 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 3.1e-16, 64.19% id in 81 aa, and to Mycobacterium leprae 50S ribosomal protein L27 ML1466 SW:RL27_MYCLE (Q9CBZ3) (88 aa) fasta scores: E(): 2.7e-24, 83.95% id in 81 aa; Belongs to the bacterial ribosomal protein bL27 family. | 0.770 |
| def-2 | rpsP | DIP1323 | DIP1532 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Similar to Mycobacterium leprae 30S ribosomal protein S16 RpsP or ML1618 or MLCB250.32 SW:RS16_MYCLE (O33014) (160 aa) fasta scores: E(): 8.3e-32, 70.39% id in 152 aa, and to Thermus aquaticus 30S ribosomal protein S16 RpsP or Rps16 SW:RS16_THETH (P80379) (88 aa) fasta scores: E(): 6.1e-11, 52.27% id in 88 aa. | 0.757 |
| def-2 | tig | DIP1323 | DIP1793 | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | FKBP-type peptidyl-prolyl cis-trans isomerase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.755 |
| fmt | DIP1321 | DIP1322 | DIP1321 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.973 |
| fmt | def-2 | DIP1322 | DIP1323 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.955 |
| fmt | rplU | DIP1322 | DIP1781 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.422 |
| fmt | rpmA | DIP1322 | DIP1780 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 3.1e-16, 64.19% id in 81 aa, and to Mycobacterium leprae 50S ribosomal protein L27 ML1466 SW:RL27_MYCLE (Q9CBZ3) (88 aa) fasta scores: E(): 2.7e-24, 83.95% id in 81 aa; Belongs to the bacterial ribosomal protein bL27 family. | 0.421 |
| rplI | def-2 | DIP2289 | DIP1323 | 50S ribosomal protein L9; Binds to the 23S rRNA. | Putative peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.793 |
| rplI | rplT | DIP2289 | DIP1162 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.996 |
| rplI | rplU | DIP2289 | DIP1781 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.990 |
