STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1361Conserved hypothetical protein; Similar to Streptomyces coelicolor possible hydrolase SC9C5.33c SWALL:Q9KXP1 (EMBL:AL357523) (235 aa) fasta scores: E(): 6.5e-25, 40.35% id in 223 aa, and to Escherichia coli hypothetical protein YcbL or B0927 SWALL:YCBL_ECOLI (SWALL:P75849) (215 aa) fasta scores: E(): 3.7e-23, 36.79% id in 212 aa. (218 aa)    
Predicted Functional Partners:
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
       0.842
hisS
histidyl-tRNA synthetase; Similar to Mycobacterium tuberculosis histidyl-tRNA synthetase HisS or Rv2580c or MT2657 or MTCY227.21 SWALL:SYH_MYCTU (SWALL:Q50641) (423 aa) fasta scores: E(): 1.6e-112, 70.4% id in 419 aa, and to Bacillus subtilis histidyl-tRNA synthetase HisS SWALL:SYH_BACSU (SWALL:O32039) (424 aa) fasta scores: E(): 3.8e-61, 45.63% id in 412 aa.
  
    0.764
DIP1363
Putative isomerase; Similar to Mycobacterium tuberculosis probable peptidyl-prolyl cis-trans isomerase B PpiB or Ppi or Rv2582 or MT2659 or MTCY227.19c SWALL:PPIB_MYCTU (SWALL:Q50639) (308 aa) fasta scores: E(): 5.5e-37, 46.23% id in 292 aa, and to Streptomyces coelicolor putative peptidyl-prolyl cis-trans isomerase SC9C5.34 SWALL:Q9KXP0 (EMBL:AL357523) (277 aa) fasta scores: E(): 3.5e-26, 37.5% id in 288 aa.
  
    0.687
DIP1748
Putative oxidase; Similar to Lactococcus lactis NADH oxidase NoxC TR:Q9CHE6 (EMBL:AE006312) (547 aa) fasta scores: E(): 5.8e-81, 44.95% id in 545 aa, and to Enterococcus faecalis NADH oxidase Nox SW:NAOX_ENTFA (P37061) (446 aa) fasta scores: E(): 3.8e-30, 27.46% id in 437 aa.
  
 0.657
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
   
 
 0.510
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
    
 
 0.452
DIP0034
Similar to Escherichia coli adenylyltransferase ThiF or B3992 SW:THIF_ECOLI (P30138) (251 aa) fasta scores: E(): 1.1e-21, 35.86% id in 237 aa.
  
 
 0.408
DIP0492
Putative molybdopterin biosynthesis protein; Similar to Synechococcus sp MTP-synthase sulfurylase MoeB TR:O54307 (EMBL:Y16560) (391 aa) fasta scores: E(): 1.1e-37, 39.56% id in 369 aa.
  
 
 0.408
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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