STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1386Putative phosphatidyltransferase; Similar to Mycobacterium tuberculosis CDC1551 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative MT2687 SWALL:AAK47003 (EMBL:AE007101) (217 aa) fasta scores: E(): 6.9e-34, 48.29% id in 205 aa, and to Mycobacterium smegmatis phosphatidylinositol synthase PgsA SWALL:Q9F7Y9 (EMBL:AF265558) (222 aa) fasta scores: E(): 8.7e-31, 47% id in 200 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (217 aa)    
Predicted Functional Partners:
DIP1458
Putative phosphatidyltransferase; Similar to Bacillus subtilis CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA SW:PGSA_BACSU (P46322) (193 aa) fasta scores: E(): 1.6e-12, 40.55% id in 180 aa, and to Escherichia coli CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA or B1912 or Z3000 or ECS2650 SW:PGSA_ECOLI (P06978) (181 aa) fasta scores: E(): 1.7e-10, 35.91% id in 181 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.969
DIP1385
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 35.4 kDa protein ML0453 or MLCl581.15c SWALL:O07148 (EMBL:Z96801) (320 aa) fasta scores: E(): 5.5e-52, 47.33% id in 300 aa, and to Streptomyces coelicolor putative acyltransferase SCL2.16c SWALL:Q9L283 (EMBL:AL137778) (311 aa) fasta scores: E(): 1.4e-37, 43.44% id in 290 aa.
 
  
 0.938
DIP1504
Putative phospholipid biosynthesis; Similar to Mycobacterium tuberculosis phosphatidate cytidylyltransferase CdsA or Rv2881c or MT2948 or MTCY274.12c SW:CDSA_MYCTU (Q10807) (306 aa) fasta scores: E(): 2.4e-51, 51.73% id in 288 aa, and to Escherichia coli phosphatidate cytidylyltransferase CdsA or Cds or B0175 or Z0186 or ECS0177 SW:CDSA_ECOLI (P06466) (249 aa) fasta scores: E(): 1.9e-14, 35.35% id in 198 aa; Belongs to the CDS family.
    
 0.925
DIP1387
Similar to Mycobacterium leprae hypothetical protein ML0455 SWALL:Q9CCU0 (EMBL:AL583918) (206 aa) fasta scores: E(): 6.3e-43, 61.49% id in 174 aa, and to Mycobacterium leprae hypothetical 20.7 kDa protein MLCl581.17c SWALL:O07150 (EMBL:Z96801) (186 aa) fasta scores: E(): 4.1e-42, 62.13% id in 169 aa.
 
  
 0.901
DIP1384
Similar to Streptomyces coelicolor putative sugar transferase SCL2.15c SWALL:Q9L284 (EMBL:AL137778) (387 aa) fasta scores: E(): 3.5e-45, 49.06% id in 375 aa, and to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT2685 SWALL:AAK47001 (EMBL:AE007101) (378 aa) fasta scores: E(): 9.2e-42, 47.89% id in 380 aa.
 
  
 0.889
DIP1383
Putative secreted protein; Similar to the N-terminal region of Mycobacterium tuberculosis CDC1551 MutT/NudIX family protein MT2684 SWALL:AAK47000 (EMBL:AE007101) (351 aa) fasta scores: E(): 1.2e-06, 42.2% id in 154 aa, and to Streptomyces coelicolor hypothetical 19.8 kDa protein SCL2.14c SWALL:Q9L285 (EMBL:AL137778) (180 aa) fasta scores: E(): 0.0099, 35.88% id in 170 aa.
 
     0.772
DIP0115
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 39.2 kDa protein SCH24.21c TR:Q9X8T5 (EMBL:AL049826) (360 aa) fasta scores: E(): 5e-111, 79.49% id in 356 aa.
 
   
 0.724
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
  
 0.715
DIP1389
Putative secreted protein; Similar to Yersinia pestis hypothetical protein YPO1856 SWALL:Q8ZF62 (EMBL:AJ414150) (434 aa) fasta scores: E(): 8.7e-30, 33.74% id in 406 aa, and to Escherichia coli hypothetical protein YcdB precursor or B1019 SWALL:YCDB_ECOLI (SWALL:P31545) (423 aa) fasta scores: E(): 2.4e-29, 32.22% id in 419 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRGFLT) at the N-terminal region.
       0.532
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD SW:PUR2_ECOLI (P15640) (429 aa) fasta scores: E(): 5.9e-59, 43.75% id in 432 aa, and to Corynebacterium ammoniagenes 5'-phosphoribosylglycinamide synthetase PurD TR:Q9RHX4 (EMBL:AB003161) (426 aa) fasta scores: E(): 1.9e-110, 69.46% id in 429 aa; Belongs to the GARS family.
  
  
 0.501
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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