STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1393Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 PilB-related protein MT2748 TR:AAK47063 (EMBL:AE007105) (136 aa) fasta scores: E(): 6.2e-39, 70.67% id in 133 aa, and to Streptomyces coelicolor putative oxidoreductase SC9B1.08 TR:Q9X828 (EMBL:AL049727) (135 aa) fasta scores: E(): 4.3e-33, 67.74% id in 124 aa; Belongs to the MsrB Met sulfoxide reductase family. (136 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.993
DIP1392
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 29.0 kDa protein ML1340 or MLC1351.23 TR:O05684 (EMBL:Z95117) (268 aa) fasta scores: E(): 1.4e-12, 30.97% id in 226 aa, and to Mycobacterium tuberculosis hypothetical 27.7 kDa protein CY441.40 Rv2671 or MT2745 or MTCY441.40 TR:AAK47060 (EMBL:Z80225) (239 aa) fasta scores: E(): 9.8e-12, 29.27% id in 222 aa.
       0.717
DIP0101
Putative membrane protein; Similar to Mycobacterium tuberculosis DipZ protein Rv2874 or MT2942 or MTCY274.05 SW:DIPZ_MYCTU (Q10801) (695 aa) fasta scores: E(): 1.6e-43, 43.65% id in 591 aa.
  
 0.575
grpE
Chaperone protein cofactor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
 
 0.556
DIP1748
Putative oxidase; Similar to Lactococcus lactis NADH oxidase NoxC TR:Q9CHE6 (EMBL:AE006312) (547 aa) fasta scores: E(): 5.8e-81, 44.95% id in 545 aa, and to Enterococcus faecalis NADH oxidase Nox SW:NAOX_ENTFA (P37061) (446 aa) fasta scores: E(): 3.8e-30, 27.46% id in 437 aa.
  
  
 0.473
rpmJ
50S ribosomal protein L36; Similar to Bacillus stearothermophilus 50S ribosomal protein L36 RpmJ SW:RL36_BACST (P07841) (37 aa) fasta scores: E(): 0.0052, 50% id in 40 aa, and to Streptomyces coelicolor putative ribosomal protein L36 SC8B3.03c TR:CAC44182 (EMBL:AL593822) (40 aa) fasta scores: E(): 2.3e-12, 85% id in 40 aa.
    
 
 0.440
cat
Catalase; Similar to Onchocerca volvulus endobacterium catalase Cat SW:CATA_ONCVE (Q27710) (482 aa) fasta scores: E(): 8e-92, 52.24% id in 490 aa.
   
  
 0.435
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.412
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.