STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1394Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2750 TR:AAK47065 (EMBL:AE007105) (231 aa) fasta scores: E(): 3e-55, 59.3% id in 231 aa, and to Streptomyces coelicolor hypothetical 28.1 kDa protein Sc1B5.02 TR:O69830 (EMBL:AL023517) (243 aa) fasta scores: E(): 5.5e-48, 54.7% id in 223 aa. (234 aa)    
Predicted Functional Partners:
hemH
Putative ferrochelatase (protoheme biosynthesis); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 0.964
DIP1395
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv2680 or MT2754 or MTV010.04 TR:O86317 (EMBL:Z96072) (210 aa) fasta scores: E(): 2.7e-38, 56.59% id in 182 aa, and to Streptomyces coelicolor hypothetical 24.7 kDa protein Sc1C3.1cC TR:O69860 (EMBL:AL023702) (238 aa) fasta scores: E(): 1.2e-22, 41.17% id in 187 aa.
 
     0.811
DIP1396
Putative ribonuclease; Similar to Mycobacterium tuberculosis CDC1551 ribonuclease D, putative MT2755 TR:AAK47070 (EMBL:AE007105) (438 aa) fasta scores: E(): 5.1e-49, 38.14% id in 409 aa, and to Escherichia coli ribonuclease D Rnd or B1804 SW:RND_ECOLI (P09155) (375 aa) fasta scores: E(): 1.2e-10, 28.36% id in 342 aa.
       0.634
hemG
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
  
 0.589
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
  
     0.528
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
    0.514
DIP1591
Putative membrane protein; Similar to Streptomyces coelicolor hypothetical 10.7 kDa protein SC4A10.11c TR:Q9S2X3 (EMBL:AL109663) (94 aa) fasta scores: E(): 2.6e-09, 34.78% id in 92 aa, and to Mycobacterium leprae possible membrane protein ML0921 TR:Q9CCE0 (EMBL:AL583920) (96 aa) fasta scores: E(): 6.7e-09, 41.57% id in 89 aa.
  
     0.452
DIP1632
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SC5F7.32 TR:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 4.8e-10, 30.45% id in 220 aa.
  
     0.450
DIP1805
Putative membrane protein; Similar to Mycobacterium leprae hypothetical protein ML1998 SW:Y102_MYCLE (P53525) (659 aa) fasta scores: E(): 2e-44, 31.72% id in 665 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0102 SW:Y102_MYCTU (Q10897) (661 aa) fasta scores: E(): 2.2e-44, 30.76% id in 650 aa.
  
     0.440
DIP2266
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative Lsr2-like protein SCD25.12c SWALL:Q9RKK8 (EMBL:AL118514) (105 aa) fasta scores: E(): 1.1e-08, 39.04% id in 105 aa, and to Mycobacterium leprae Lsr2 protein precursor or ML0234 SWALL:LSR2_MYCLE (SWALL:P24094) (112 aa) fasta scores: E(): 2.4, 26.95% id in 115 aa.
  
     0.425
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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