STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1395Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv2680 or MT2754 or MTV010.04 TR:O86317 (EMBL:Z96072) (210 aa) fasta scores: E(): 2.7e-38, 56.59% id in 182 aa, and to Streptomyces coelicolor hypothetical 24.7 kDa protein Sc1C3.1cC TR:O69860 (EMBL:AL023702) (238 aa) fasta scores: E(): 1.2e-22, 41.17% id in 187 aa. (193 aa)    
Predicted Functional Partners:
DIP1396
Putative ribonuclease; Similar to Mycobacterium tuberculosis CDC1551 ribonuclease D, putative MT2755 TR:AAK47070 (EMBL:AE007105) (438 aa) fasta scores: E(): 5.1e-49, 38.14% id in 409 aa, and to Escherichia coli ribonuclease D Rnd or B1804 SW:RND_ECOLI (P09155) (375 aa) fasta scores: E(): 1.2e-10, 28.36% id in 342 aa.
 
    0.916
DIP1394
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2750 TR:AAK47065 (EMBL:AE007105) (231 aa) fasta scores: E(): 3e-55, 59.3% id in 231 aa, and to Streptomyces coelicolor hypothetical 28.1 kDa protein Sc1B5.02 TR:O69830 (EMBL:AL023517) (243 aa) fasta scores: E(): 5.5e-48, 54.7% id in 223 aa.
 
     0.811
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.758
DIP1642
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rvv2219 precursor or MT2276 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 2.4e-36, 42.8% id in 250 aa.
  
     0.746
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.712
DIP0004
Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 17.5 kDa protein TR:Q9L7L4 (EMBL:AF222789) (166 aa) fasta scores: E(): 5.6e-18, 45.45% id in 143 aa.
  
     0.710
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
  
     0.681
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.679
DIP1921
Similar to Corynebacterium ammoniagenes hypothetical protein Orf3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.5e-26, 61.15% id in 121 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0807 TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 2.3e-24, 57.48% id in 127 aa.
  
     0.666
DIP1445
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 49.8 kDa protein MT2802 TR:AAK47120 (EMBL:AE007108) (450 aa) fasta scores: E(): 5.4e-66, 48.52% id in 441 aa.
  
     0.651
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.