STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1398Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 43.2 kDa protein Rv2689c or MT2763 or MTCY05A6.10c TR:O07191 (EMBL:Z96072) (405 aa) fasta scores: E(): 3.4e-27, 40.39% id in 401 aa, and to Streptomyces coelicolor SC10A5.06 protein TR:O54099 (EMBL:AL021529) (458 aa) fasta scores: E(): 1e-20, 31.59% id in 440 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (420 aa)    
Predicted Functional Partners:
DIP1249
Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
   
  
 0.660
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.629
DIP1399
Conserved hypothetical protein; Similar to Mycobacterium leprae U1764K ML1029 TR:Q49993 (EMBL:U15181) (273 aa) fasta scores: E(): 1e-24, 38.88% id in 234 aa, and to Mycobacterium tuberculosis hypothetical 27.2 kDa protein Rv2696c or MTCY05A6.17c TR:O07198 (EMBL:Z96072) (259 aa) fasta scores: E(): 1.5e-24, 37.34% id in 241 aa.
       0.604
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.556
DIP1401
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 17.6 kDa protein Rv2698 or MTCY05A6.19 TR:O07200 (EMBL:Z96072) (161 aa) fasta scores: E(): 1.9e-21, 45.28% id in 159 aa, and to Mycobacterium leprae U1764I ML12027 TR:Q49991 (EMBL:U15181) (157 aa) fasta scores: E(): 3e-19, 41.77% id in 158 aa.
       0.506
DIP1321
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.490
recN
DNA repair protein; May be involved in recombinational repair of damaged DNA.
  
    0.476
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
 
    0.459
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.455
trmB
Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.455
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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