STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1399Conserved hypothetical protein; Similar to Mycobacterium leprae U1764K ML1029 TR:Q49993 (EMBL:U15181) (273 aa) fasta scores: E(): 1e-24, 38.88% id in 234 aa, and to Mycobacterium tuberculosis hypothetical 27.2 kDa protein Rv2696c or MTCY05A6.17c TR:O07198 (EMBL:Z96072) (259 aa) fasta scores: E(): 1.5e-24, 37.34% id in 241 aa. (239 aa)    
Predicted Functional Partners:
DIP1401
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 17.6 kDa protein Rv2698 or MTCY05A6.19 TR:O07200 (EMBL:Z96072) (161 aa) fasta scores: E(): 1.9e-21, 45.28% id in 159 aa, and to Mycobacterium leprae U1764I ML12027 TR:Q49991 (EMBL:U15181) (157 aa) fasta scores: E(): 3e-19, 41.77% id in 158 aa.
 
     0.732
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.718
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.697
DIP0865
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 39.5 kDa protein Rv0996 or MTCI237.10 TR:O05579 (EMBL:Z94752) (358 aa) fasta scores: E(): 1.8e-13, 30.27% id in 370 aa.
  
     0.668
DIP0716
Putative secreted protein; Low similarity to Mycobacterium leprae putative membrane protein ML0810 TR:Q9CCH4 (EMBL:AL583919) (407 aa) fasta scores: E(): 1.1e-21, 26.81% id in 414 aa.
  
     0.666
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
 
     0.660
DIP0567
Similar to Mycobacterium leprae hypothetical protein ML0370 TR:Q9CCV6 (EMBL:AL583918) (289 aa) fasta scores: E(): 6.4e-34, 42.46% id in 252 aa.
  
     0.629
DIP0639
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa.
  
     0.608
DIP1921
Similar to Corynebacterium ammoniagenes hypothetical protein Orf3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.5e-26, 61.15% id in 121 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0807 TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 2.3e-24, 57.48% id in 127 aa.
  
     0.603
DIP1784
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv2446c TR:O53173 (EMBL:AL021246) (123 aa) fasta scores: E(): 1.5e-07, 31.35% id in 118 aa, and to Mycobacterium leprae conserved membrane protein ML1470 TR:Q9CBY9 (EMBL:AL583922) (123 aa) fasta scores: E(): 4.9e-07, 30.46% id in 128 aa.
  
     0.601
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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