STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1408Conserved hypothetical protein; Similar, but shorter in its N-terminal region, to Mycobacterium tuberculosis hypothetical 65.8 kDa protein Rv2917 or MT2985 or MTCY338.05 SW:YT17_MYCTU (Q10966) (602 aa) fasta scores: E(): 6.4e-116, 62.39% id in 569 aa, and to Mycobacterium leprae hypothetical 65.2 kDa protein ML1624 or MLCB250.18c SW:YT17_MYCLE (O33011) (596 aa) fasta scores: E(): 8.8e-113, 60.28% id in 569 aa. (569 aa)    
Predicted Functional Partners:
DIP1409
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2781 TR:AAK47097 (EMBL:AE007107) (82 aa) fasta scores: E(): 1.4e-17, 65.78% id in 76 aa, and to Mycobacterium leprae U1764c ML1016 TR:Q49984 (EMBL:U15181) (107 aa) fasta scores: E(): 2.8e-16, 65.78% id in 76 aa.
       0.842
DIP1445
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 49.8 kDa protein MT2802 TR:AAK47120 (EMBL:AE007108) (450 aa) fasta scores: E(): 5.4e-66, 48.52% id in 441 aa.
  
  
 0.796
DIP1411
Putative transferase; Similar to Streptomyces coelicolor putative transferase SCH5.08c TR:Q9X911 (EMBL:AL035636) (505 aa) fasta scores: E(): 3.6e-46, 35.44% id in 522 aa; Belongs to the methyltransferase superfamily.
 
 
   0.777
DIP1859
DeaD/DeaH family helicase; Similar to Escherichia coli probable ATP-dependent helicase DinG SW:DING_ECOLI (P27296) (716 aa) fasta scores: E(): 5.6e-15, 27.57% id in 689 aa, and to Mycobacterium tuberculosis probable ATP-dependent helicase DinG homologue Rv1329c SW:DING_MYCTU (Q10640) (664 aa) fasta scores: E(): 2.2e-131, 55.84% id in 659 aa.
   
 0.763
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.756
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.745
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.744
DIP1278
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 29.4 kDa protein SCC77.24 SWALL:Q9RDD4 (EMBL:AL136503) (274 aa) fasta scores: E(): 1.3e-46, 50.57% id in 259 aa, and to Mycobacterium tuberculosis hypothetical 30.5 kDa protein Rv2033c or MTV018.20 SWALL:O53477 (EMBL:AL021899) (280 aa) fasta scores: E(): 6.7e-37, 46.78% id in 280 aa.
  
     0.734
DIP1410
Putative membrane protein; No significant database matches.
       0.706
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.657
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.