STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1409Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2781 TR:AAK47097 (EMBL:AE007107) (82 aa) fasta scores: E(): 1.4e-17, 65.78% id in 76 aa, and to Mycobacterium leprae U1764c ML1016 TR:Q49984 (EMBL:U15181) (107 aa) fasta scores: E(): 2.8e-16, 65.78% id in 76 aa. (79 aa)    
Predicted Functional Partners:
DIP1408
Conserved hypothetical protein; Similar, but shorter in its N-terminal region, to Mycobacterium tuberculosis hypothetical 65.8 kDa protein Rv2917 or MT2985 or MTCY338.05 SW:YT17_MYCTU (Q10966) (602 aa) fasta scores: E(): 6.4e-116, 62.39% id in 569 aa, and to Mycobacterium leprae hypothetical 65.2 kDa protein ML1624 or MLCB250.18c SW:YT17_MYCLE (O33011) (596 aa) fasta scores: E(): 8.8e-113, 60.28% id in 569 aa.
       0.842
DIP1410
Putative membrane protein; No significant database matches.
       0.706
DIP1411
Putative transferase; Similar to Streptomyces coelicolor putative transferase SCH5.08c TR:Q9X911 (EMBL:AL035636) (505 aa) fasta scores: E(): 3.6e-46, 35.44% id in 522 aa; Belongs to the methyltransferase superfamily.
       0.646
DIP1412
Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality.
       0.641
DIP1407
Putative membrane protein; No significant database matches.
       0.593
DIP1614
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2175c or MTV021.08c TR:O53509 (EMBL:AL021957) (146 aa) fasta scores: E(): 7.8e-08, 40.45% id in 131 aa.
  
     0.593
DIP0685
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.6 kDa protein Rv3259 or MTV015.04 TR:O53352 (EMBL:AL021840) (139 aa) fasta scores: E(): 4.2e-21, 50% id in 136 aa.
  
     0.585
sigB
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.565
DIP1610
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.9 kDa protein Rv2170 or MTV021.03 TR:O53504 (EMBL:AL021957) (206 aa) fasta scores: E(): 3.4e-16, 35.14% id in 202 aa.
  
     0.531
ag84
Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273).
  
     0.521
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.