STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1417Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2787 TR:AAK47103 (EMBL:AE007107) (324 aa) fasta scores: E(): 2.1e-45, 45.09% id in 306 aa, and to Streptomyces coelicolor conserved hypothetical protein SCI52.04 TR:Q9ADA5 (EMBL:AL590507) (333 aa) fasta scores: E(): 4.2e-12, 26.64% id in 304 aa. (313 aa)    
Predicted Functional Partners:
DIP1418
Putative helicase; Similar in its full length to Streptomyces coelicolor putative helicase SCG8A.06 TR:Q9KZJ3 (EMBL:AL353863) (854 aa) fasta scores: E(): 2.1e-184, 56.4% id in 828 aa, and to the C-terminal region of Schizosaccharomyces pombe putative helicase SPAC6F12.16c SW:YDVG_SCHPO (O14232) (1117 aa) fasta scores: E(): 1.5e-13, 27.64% id in 445 aa.
       0.773
DIP1874
Similar to Streptomyces coelicolor hypothetical protein SCJ12.09c TR:Q9RI49 (EMBL:AL109989) (146 aa) fasta scores: E(): 7.2e-10, 38.68% id in 137 aa. C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv3129 TR:O05803 (EMBL:Z95150) (110 aa) fasta scores: E(): 5.1e-11, 47.77% id in 90 aa.
  
    0.736
DIP1416
Hypothetical protein; No significant database matches.
       0.638
DIP1205
Putative merR-family regulatory protein; Similar to Streptomyces coelicolor hypothetical 26.5 kDa protein SC1A8A.03c SWALL:Q9KZP9 (EMBL:AL353861) (246 aa) fasta scores: E(): 1.4e-27, 41.44% id in 222 aa, and to Mycobacterium tuberculosis hypothetical 26.4 kDa protein Rv1828 or MT1876 or MTCY1A11.15c SWALL:YI28_MYCTU (SWALL:Q50605) (247 aa) fasta scores: E(): 1.2e-14, 40.25% id in 236 aa.
  
     0.625
whiB-2
Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.598
DIP1300
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1456c or MT1503 or MTV007.03C SWALL:AAK45767 (EMBL:AL021184) (311 aa) fasta scores: E(): 3.7e-43, 43.75% id in 304 aa, and to Streptomyces coelicolor putative integral membrane transport protein SCC22.12 SWALL:Q9XAC6 (EMBL:AL096839) (356 aa) fasta scores: E(): 6.9e-24, 33.01% id in 312 aa, and low similarity to Bacillus firmus cytochrome aa3 controlling protein ctaA SWALL:CTAA_BACFI (SWALL:Q04443) (297 aa) fasta scores: E(): 0.0021, 21.42% id in 266 aa.
  
     0.563
DIP0784
Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
     0.529
whiB-3
Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.524
clpS
Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
     0.517
nucS
Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.493
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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