STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1457Putative competence-damage related protein; Similar to Streptomyces coelicolor hypothetical 18.5 kDa protein Sc7C7.09 TR:O86814 (EMBL:AL031031) (181 aa) fasta scores: E(): 1.7e-13, 36.87% id in 160 aa, and to the C-terminal region of Streptococcus pneumoniae putative competence-damage protein CinA or Exp10 or SP1941 SW:CINA_STRPN (P54184) (418 aa) fasta scores: E(): 4.3e-15, 47.86% id in 117 aa. (165 aa)    
Predicted Functional Partners:
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.938
DIP1858
Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.926
nadC
Similar to Mycobacterium tuberculosis nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC or Rv1596 or MT1632 or MTCY336.08c SWALL:NADC_MYCTU (SWALL:O06594) (285 aa) fasta scores: E(): 2.1e-43, 51.09% id in 274 aa, and to Salmonella typhimurium nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC or STM0145 SWALL:NADC_SALTY (SWALL:P30012) (296 aa) fasta scores: E(): 1.6e-34, 41.17% id in 272 aa; Belongs to the NadC/ModD family.
     
 0.909
DIP0725
Putative hydrolase; Similar to C-terminal region of Vibrio cholerae NADH pyrophosphatase NudC or VC0331 SW:NUDC_VIBCH (Q9KV27) (269 aa) fasta scores: E(): 2.3e-11, 32.75% id in 174 aa.
     
  0.900
DIP1458
Putative phosphatidyltransferase; Similar to Bacillus subtilis CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA SW:PGSA_BACSU (P46322) (193 aa) fasta scores: E(): 1.6e-12, 40.55% id in 180 aa, and to Escherichia coli CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA or B1912 or Z3000 or ECS2650 SW:PGSA_ECOLI (P06978) (181 aa) fasta scores: E(): 1.7e-10, 35.91% id in 181 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.853
DIP1456
Putative DNA-binding protein; Similar to Mycobacterium tuberculosis CDC1551 DNA-binding protein, putative MT2816 TR:AAK47136 (EMBL:AE007109) (112 aa) fasta scores: E(): 1.2e-09, 56.16% id in 73 aa, and to Streptomyces coelicolor hypothetical 13.6 kDa protein SC7C7.10 TR:O86815 (EMBL:AL031031) (126 aa) fasta scores: E(): 1.1e-08, 49.39% id in 83 aa.
     
 0.727
DIP1459
Conserved hypothetical protein; Similar to Agrobacterium tumefaciens StrC58 AGR_C_4802p TR:AAK88371 (EMBL:AE008178) (97 aa) fasta scores: E(): 2.2e-05, 33.67% id in 98 aa, and to Rhizobium loti MSR4226 protein TR:Q98EI5 (EMBL:AP003003) (98 aa) fasta scores: E(): 6e-05, 32.63% id in 95 aa.
       0.662
DIP1455
Conserved hypothetical protein; Similar in its full length to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SW:35KD_MYCTU (P31511) (270 aa) fasta scores: E(): 1.2e-51, 75.8% id in 248 aa, N-terminal region to Mycobacterium leprae B2235_C2_187 MLCB33.06c TR:Q49840 (EMBL:U00019) (167 aa) fasta scores: E(): 2.9e-27, 72.1% id in 147 aa, and C-terminal region to Mycobacterium leprae B2235_C3_214 MLCB33.05c TR:Q49845 (EMBL:U00019) (114 aa) fasta scores: E(): 3.4e-12, 58.18% id in 110 aa.
       0.580
rpsP
Similar to Mycobacterium leprae 30S ribosomal protein S16 RpsP or ML1618 or MLCB250.32 SW:RS16_MYCLE (O33014) (160 aa) fasta scores: E(): 8.3e-32, 70.39% id in 152 aa, and to Thermus aquaticus 30S ribosomal protein S16 RpsP or Rps16 SW:RS16_THETH (P80379) (88 aa) fasta scores: E(): 6.1e-11, 52.27% id in 88 aa.
 
    0.467
DIP1552
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
   
    0.420
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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