Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1460Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCM1.25c TR:Q9RD18 (EMBL:AL133422) (316 aa) fasta scores: E(): 3.1e-54, 48.93% id in 327 aa, and to Xylella fastidiosa export protein XF0406 TR:Q9PG96 (EMBL:AE003892) (319 aa) fasta scores: E(): 1.3e-39, 39.43% id in 317 aa. (335 aa)    
Predicted Functional Partners:
DIP1461
Putative cell division protein; Similar to Streptomyces coelicolor FtsK homolog SC7C7.05 TR:O86810 (EMBL:AL031031) (929 aa) fasta scores: E(): 2.1e-106, 50.17% id in 837 aa, and similar to C-terminal region of Escherichia coli cell division protein FtsK or B0890 SW:FTSK_ECOLI (P46889) (1329 aa) fasta scores: E(): 6.5e-34, 39.14% id in 700 aa.
     
 0.606
thyX
Conserved hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
 
     0.532
DIP1462
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 23.6 kDa protein SC4G6.14 TR:Q9S2U0 (EMBL:AL096884) (211 aa) fasta scores: E(): 1.4e-09, 31.86% id in 204 aa, and to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1929c or MTCY09F9.35 TR:P95285 (EMBL:Z84498) (214 aa) fasta scores: E(): 4.3e-07, 32.71% id in 217 aa.
       0.531
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.487
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
       0.487
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
       0.459
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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