Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIP1469Similar to Rhizobium meliloti putative nucleoside hydrolase protein SMC01105 TR:CAC41852 (EMBL:AL591783) (314 aa) fasta scores: E(): 2.3e-28, 33.96% id in 315 aa, and to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SW:IUNH_CRIFA (Q27546) (314 aa) fasta scores: E(): 4.6e-26, 33.33% id in 315 aa. (319 aa)    
Predicted Functional Partners:
ribF
Riboflavin biosynthesis protein; Similar to Corynebacterium ammoniagenes riboflavin biosynthesis protein RibF [includes: riboflavin kinase (EC 2.7.1.26); FMN adenylyltransferase (EC 2.7.7.2)] SW:RIBF_CORAM (Q59263) (338 aa) fasta scores: E(): 9.6e-66, 54.23% id in 319 aa, and to Escherichia coli riboflavin biosynthesis protein RibF [includes: riboflavin kinase (EC 2.7.1.26); FMN adenylyltransferase (EC 2.7.7.2)] or B0025 or Z0029 or ECS0028 SW:RIBF_ECOLI (P08391) (313 aa) fasta scores: E(): 5.3e-19, 30.86% id in 311 aa.
       0.691
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.652
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.543
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
       0.520
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.447
DIP1752
Putative antibiotic resistance related transport protein; Similar to Lactococcus lactis multidrug transporter YqiA TR:Q9CF47 (EMBL:AE006394) (476 aa) fasta scores: E(): 1.5e-87, 58.69% id in 460 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.8e-15, 24.88% id in 422 aa.
 
  
 0.435
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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