STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1473Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 37.6 kDa protein Rv2795c or MTV002.60c TR:O33337 (EMBL:AL008967) (324 aa) fasta scores: E(): 1e-22, 46.79% id in 265 aa, and to Streptomyces coelicolor hypothetical 33.5 kDa protein SC5A7.22 TR:O88028 (EMBL:AL031107) (295 aa) fasta scores: E(): 1.1e-17, 41.63% id in 257 aa. (268 aa)    
Predicted Functional Partners:
DIP1472
Putative transferase; Similar to Streptomyces coelicolor hypothetical 24.5 kDa protein Sc5A7.23 TR:O88029 (EMBL:AL031107) (226 aa) fasta scores: E(): 6.2e-26, 45.77% id in 201 aa, and to Streptomyces verticillus phosphopantetheinyl transferase PptA TR:Q9F0Q6 (EMBL:AF210311) (246 aa) fasta scores: E(): 1.6e-24, 44.04% id in 193 aa.
 
  
 0.939
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
    
 
 0.767
DIP1474
Putative DNA-damage inducible protein; Similar to Mycobacterium tuberculosis hypothetical 44.8 kDa protein DinF or Rv2836c or MTCY16B7.06 TR:P71616 (EMBL:Z81331) (439 aa) fasta scores: E(): 1e-72, 50.59% id in 423 aa, and to Rhizobium loti DNA-damage-inducible protein MLR5680 TR:Q98B90 (EMBL:AP003007) (471 aa) fasta scores: E(): 1.9e-19, 30.07% id in 429 aa.
       0.750
DIP1475
Conserved hypothetical protein; Similar to, although shorter in its N-terminal region than, Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv2837c or MTCY16B7.05 TR:P71615 (EMBL:Z81331) (336 aa) fasta scores: E(): 8.5e-29, 34.84% id in 287 aa, and to Clostridium acetobutylicum exopolyphosphatase family protein CAC1804 TR:AAK79769 (EMBL:AE007689) (321 aa) fasta scores: E(): 1.9e-19, 33.19% id in 235 aa.
       0.750
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
 
   
 0.722
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
 
  
 0.686
rbfA
Putative ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.637
DIP1116
Putative exported esterase/hydrolase; Similar to Mycobacterium tuberculosis CDC1551 esterase, putative MT3397 TR:AAK47740 (EMBL:AE007148) (304 aa) fasta scores: E(): 5.3e-09, 30.57% id in 242 aa, and to Piromyces equi cinnamoyl ester hydrolase EstA TR:Q9Y871 (EMBL:AF164516) (536 aa) fasta scores: E(): 1.2e-06, 25.19% id in 258 aa, and to Pseudomonas fluorescens esterase D XynD TR:Q51815 (EMBL:X58956) (583 aa) fasta scores: E(): 5.8e-06, 27.37% id in 274 aa.
  
     0.608
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.543
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
 
     0.526
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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