Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DIP1478Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2906 TR:AAK47232 (EMBL:AE007115) (99 aa) fasta scores: E(): 1.3e-06, 43.67% id in 87 aa, and to Rhizobium meliloti hypothetical protein SMC02913 TR:CAC41675 (EMBL:AL591783) (230 aa) fasta scores: E(): 0.00061, 32.14% id in 112 aa. (110 aa)    
Predicted Functional Partners:
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
  
 0.920
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.910
nusA
Putative N utilization related protein; Participates in both transcription termination and antitermination.
  
    0.903
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
    0.734
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
    0.728
rbfA
Putative ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.650
DIP1481
Putative secreted protein; No significant database matches.
       0.534
DIP1474
Putative DNA-damage inducible protein; Similar to Mycobacterium tuberculosis hypothetical 44.8 kDa protein DinF or Rv2836c or MTCY16B7.06 TR:P71616 (EMBL:Z81331) (439 aa) fasta scores: E(): 1e-72, 50.59% id in 423 aa, and to Rhizobium loti DNA-damage-inducible protein MLR5680 TR:Q98B90 (EMBL:AP003007) (471 aa) fasta scores: E(): 1.9e-19, 30.07% id in 429 aa.
   
   0.525
DIP1475
Conserved hypothetical protein; Similar to, although shorter in its N-terminal region than, Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv2837c or MTCY16B7.05 TR:P71615 (EMBL:Z81331) (336 aa) fasta scores: E(): 8.5e-29, 34.84% id in 287 aa, and to Clostridium acetobutylicum exopolyphosphatase family protein CAC1804 TR:AAK79769 (EMBL:AE007689) (321 aa) fasta scores: E(): 1.9e-19, 33.19% id in 235 aa.
  
    0.520
DIP1472
Putative transferase; Similar to Streptomyces coelicolor hypothetical 24.5 kDa protein Sc5A7.23 TR:O88029 (EMBL:AL031107) (226 aa) fasta scores: E(): 6.2e-26, 45.77% id in 201 aa, and to Streptomyces verticillus phosphopantetheinyl transferase PptA TR:Q9F0Q6 (EMBL:AF210311) (246 aa) fasta scores: E(): 1.6e-24, 44.04% id in 193 aa.
       0.475
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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