STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1486Putative cobalamin synthesis related protein; Similar to Staphylococcus aureus (strain N315) hypothetical protein SA0410 or SAV0450 TR:BAB56612 (EMBL:AP003130) (400 aa) fasta scores: E(): 4.2e-50, 48.16% id in 326 aa, and to Pseudomonas denitrificans CobW protein SW:COBW_PSEDE (P29937) (353 aa) fasta scores: E(): 1.1e-19, 29.22% id in 349 aa. (374 aa)    
Predicted Functional Partners:
DIP1488
Similar to Mycobacterium tuberculosis cobyrinic acid A,C-diamide synthase CobB or Rv2848c or MT2914 or MTCY24A1.09 SW:COBB_MYCTU (O05811) (457 aa) fasta scores: E(): 1.1e-80, 54.54% id in 429 aa, and to Salmonella typhimurium cobyrinic acid A,C-diamide synthase CbiA SW:CBIA_SALTY (P29946) (459 aa) fasta scores: E(): 5.8e-30, 36.4% id in 445 aa.
     
 0.759
DIP1487
Putative DNA repair related protein; Similar to Escherichia coli methylated-DNA--protein-cysteine methyltransferase Ogt or B1335 SW:OGT_ECOLI (P09168) (171 aa) fasta scores: E(): 8.7e-12, 32.7% id in 159 aa, and to Salmonella typhimurium methylated-DNA--protein-cysteine methyltransferase Ogt or STM1659 or STY1405 SW:OGT_SALTY (P37429) (171 aa) fasta scores: E(): 1e-10, 31.44% id in 159 aa.
       0.737
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.732
DIP0173
Putative membrane protein; Similar to Neisseria meningitidis putative periplasmic binding protein NMA0789 SWALL:Q9JVL4 (EMBL:AL162754) (308 aa) fasta scores: E(): 2.7e-24, 31.71% id in 309 aa, and to Treponema pallidum periplasmic zinc-binding protein TroA or TroMP1 or TP0163 SWALL:TROA_TREPA (SWALL:P96116) (308 aa) fasta scores: E(): 2.5e-16, 33.12% id in 317 aa, and to Streptococcus pyogenes zinc-binding protein precursor AdcA or SPY0714 SWALL:Q9A0L9 (EMBL:AE006523) (515 aa) fasta scores: E(): 2.5e-16, 28.85% id in 298 aa Note: Also similar to the upstream DIP0169, (321 aa) E(): 4.5e [...]
  
  
 0.716
DIP0438
Putative secreted protein; C-terminal similar to Bacillus halodurans surface adhesin A precursor PsaA or BH0516 TR:Q9KFG3 (EMBL:AP001508) (300 aa) fasta scores: E(): 2.9e-14, 34.09% id in 176 aa; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.672
DIP1489
Putative cobalamin adenosyltransferase; Similar to Mycobacterium tuberculosis CDC1551 Cob MT2915 TR:AAK47241 (EMBL:AE007116) (207 aa) fasta scores: E(): 5.1e-60, 68.9% id in 209 aa, and to Pseudomonas denitrificans CobO SW:COBO_PSEDE (P29930) (213 aa) fasta scores: E(): 5.8e-13, 41.75% id in 182 aa.
     
 0.627
DIP0169
Putative secreted protein; Similar to Treponema pallidum periplasmic zinc-binding protein TroA or TroMP1 or TP0163 SWALL:TROA_TREPA (SWALL:P96116) (308 aa) fasta scores: E(): 4.2e-29, 35.27% id in 292 aa, and to Streptococcus pneumoniae manganese ABC transporter substrate-binding lipoprotein precursor PsaA or SP1650 SWALL:P72538 (EMBL:U53509) (309 aa) fasta scores: E(): 1.6e-19, 28.47% id in 309 aa, and to Streptococcus gordonii challis coagregation-mediating adhesin precursor ScaA SW:ADHS_STRGC () (310 aa) fasta scores: E(): 1.9e-20, 30.15% id in 315 aa. Note: Also similar to the down [...]
  
  
 0.614
rpmB2
Similar to Mycobacterium tuberculosis 50S ribosomal protein L28-2 RpmB2 or Rv2058c or MT2118 or MTCY63A.02 SW:R28B_MYCTU (O86357) (78 aa) fasta scores: E(): 7.7e-22, 70.51% id in 78 aa; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.559
mapA
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
   0.544
mapB
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
   0.544
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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