STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1497Putative secreted penicillin-binding protein; Similar to Mycobacterium tuberculosis penecillin binding protein Rv2864c or MTV003.10c TR:O33346 (EMBL:AL008883) (603 aa) fasta scores: E(): 1.9e-81, 42.81% id in 612 aa, and to Staphylococcus aureus beta-lactam-inducible penicillin-binding protein Pbp SW:PBP_STAAU (P07944) (670 aa) fasta scores: E(): 2.3e-07, 21.04% id in 632 aa. (618 aa)    
Predicted Functional Partners:
DIP0298
Putative penicillin-binding secreted protein; Similar to Mycobacterium leprae Pbp1 Pon1 SWALL:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 4.9e-130, 48.08% id in 757 aa, and to Mycobacterium tuberculosis CDC1551 penicillin-binding protein 1 MT3784 TR:AAK48151 (EMBL:AE007176) (810 aa) fasta scores: E(): 4.8e-134, 48.75% id in 761 aa.
  
 
 
 0.855
DIP2294
Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa.
  
 
 
 0.829
DIP1599
Putative cell division protein; Similar to Corynebacterium glutamicum FtsW protein TR:Q9L4H4 (EMBL:AJ242646) (490 aa) fasta scores: E(): 9.6e-78, 48.85% id in 481 aa, and to Escherichia coli cell division protein FtsW or B0089 or Z0099 or ECS0093 SW:FTSW_ECOLI (P16457) (414 aa) fasta scores: E(): 1e-21, 32.53% id in 375 aa; Belongs to the SEDS family.
 
 
 0.775
ftsW
Similar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa; Belongs to the SEDS family.
 
 
 0.753
mapB
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.750
DIP1596
Putative cell division protein precursor; Essential cell division protein.
 
 
 0.731
DIP1501
Putative membrane protein; No significant database matches.
 
     0.700
gcpE
Conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.679
DIP2265
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.8 kDa protein Rv3850 or MTCY01A6.18C SWALL:P96227 (EMBL:Z83864) (218 aa) fasta scores: E(): 7.9e-15, 34.1% id in 217 aa.
  
     0.662
cobQ
Putative cobric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.660
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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