Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Score
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (269 aa)    
Predicted Functional Partners:
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.986
tsf
Elongation factor TS; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.953
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 
 0.944
pyrF
Similar to Mycobacterium leprae orotidine 5'-phosphate decarboxylase PyrF or ML0537 SWALL:Q9CCR1 (EMBL:AL583918) (282 aa) fasta scores: E(): 7.5e-48, 53.13% id in 271 aa, and to Streptomyces coelicolor orotidine 5'-phosphate decarboxylase PyrF or SC9C5.05c SWALL:Q9KXR8 (EMBL:AL357523) (278 aa) fasta scores: E(): 2.9e-44, 48.14% id in 270 aa; Belongs to the OMP decarboxylase family. Type 2 subfamily.
   
 
 0.927
ndk
Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.927
pyrR
Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
     
 0.922
rpsB
30S ribosomal protein S2; Similar to Mycobacterium tuberculosis 30S ribosomal protein S2 RpsB or Rv2890c or MT2958 or MTCY274.21c SW:RS2_MYCTU (Q10796) (287 aa) fasta scores: E(): 1.4e-68, 70.94% id in 265 aa, and to Escherichia coli 30S ribosomal protein S2 RpsB or B0169 or Z0180 or ECS0171 SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 2.8e-40, 50.22% id in 225 aa; Belongs to the universal ribosomal protein uS2 family.
 
  
 0.918
DIP0654
Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
DIP1693
Putative N-acetylglucosamine related protein; Similar to Streptomyces coelicolor conserved hypothetical protein SCE20.17c TR:Q9RDA8 (EMBL:AL136058) (259 aa) fasta scores: E(): 4.9e-62, 65.86% id in 249 aa, and to Escherichia coli NagD protein or B0675 or Z0822 or ECS0705 SW:NAGD_ECOLI (P15302) (250 aa) fasta scores: E(): 1e-37, 43.02% id in 251 aa; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  
 0.834
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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