Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1509Putative secreted protein; Similar to the N-terminal region of Mycobacterium tuberculosis hypothetical 25.8 kDa protein Rv2891 precursor or MT2958.2 or MTCY274.22 SW:YS91_MYCTU (Q10812) (249 aa) fasta scores: E(): 2.1e-14, 39.05% id in 169 aa. (177 aa)    
Predicted Functional Partners:
DIP1281
Putative invasion protein; Similar to Mycobacterium tuberculosis hypothetical 49.8 kDa protein Rv1477 or MT1524 or MTV007.24 SWALL:O53168 (EMBL:AL021184) (472 aa) fasta scores: E(): 3.5e-21, 31.88% id in 577 aa, and C-terminal half similar to the whole length of Mycobacterium tuberculosis hypothetical invasion protein Inv1 SWALL:O33171 (EMBL:AF006054) (277 aa) fasta scores: E(): 1e-17, 39.5% id in 281 aa. Note: Contains two possible colied-coil region at residues 102..130 and 182..360.
  
  
 0.552
rpsB
30S ribosomal protein S2; Similar to Mycobacterium tuberculosis 30S ribosomal protein S2 RpsB or Rv2890c or MT2958 or MTCY274.21c SW:RS2_MYCTU (Q10796) (287 aa) fasta scores: E(): 1.4e-68, 70.94% id in 265 aa, and to Escherichia coli 30S ribosomal protein S2 RpsB or B0169 or Z0180 or ECS0171 SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 2.8e-40, 50.22% id in 225 aa; Belongs to the universal ribosomal protein uS2 family.
       0.539
DIP0836
Conserved hypothetical protein; Similar to C-terminal region of Mycobacterium tuberculosis CDC1551 peptidase, M23/M37 family MT0977 TR:AAK45225 (EMBL:AE006983) (332 aa) fasta scores: E(): 2.2e-33, 45.25% id in 232 aa.
      
 0.522
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.521
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
      
 0.499
DIP1514
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.2 kDa protein Rv2901c or MT2969 or MTCY274.32c SW:YT01_MYCTU (Q10822) (101 aa) fasta scores: E(): 3.7e-31, 70.29% id in 101 aa, and to Streptomyces coelicolor hypothetical 12.3 kDa protein SC2E1.18 TR:O69889 (EMBL:AL023797) (102 aa) fasta scores: E(): 2.9e-27, 67% id in 100 aa.
 
     0.491
tsf
Elongation factor TS; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
       0.463
DIP0538
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 46.2 kDa protein SC5F8.10c TR:Q9K4L4 (EMBL:AL357613) (410 aa) fasta scores: E(): 2.1e-74, 50% id in 394 aa.
  
     0.450
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.430
csp1
Putative secreted antigen; Similar to Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.8e-147, 57.51% id in 659 aa, and similar to but longer than Mycobacterium intracellulare antigen 85-B precursor FbpB SW:A85B_MYCIT (Q49575) (330 aa) fasta scores: E(): 1.8e-29, 37.18% id in 320 aa.
  
  
 0.430
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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