STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerCPutative integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (302 aa)    
Predicted Functional Partners:
DIP0697
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.5 kDa protein Rv3242c or MTCY20B11.17c TR:O05887 (EMBL:Z95121) (213 aa) fasta scores: E(): 8.3e-21, 41.5% id in 212 aa.
   
    0.906
DIP1349
Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
   
  
 0.853
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.831
DIP0245
Putative prephenate dehydrogenase; Similar to Mycobacterium tuberculosis CDC1551 prephenate dehydrogenase MT3861 TR:AAK48225 (EMBL:AE007181) (323 aa) fasta scores: E(): 5.5e-49, 52.31% id in 281 aa, and to Bacillus subtilis prephenate dehydrogenase TyrA SW:TYRA_BACSU (P20692) (372 aa) fasta scores: E(): 2.7e-15, 31.9% id in 279 aa.
  
    0.746
DIP0707
Conserved hypothetical protein; Similar to Halobacterium sp VNG0686c TR:Q9HRI0 (EMBL:AE005014) (229 aa) fasta scores: E(): 4.5e-12, 35.51% id in 245 aa; Belongs to the SOS response-associated peptidase family.
   
    0.744
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
   
    0.744
DIP1511
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 40.1 kDa protein Rv2896c or MT2964 or MTCY274.27C SW:YS96_MYCTU (Q10817) (389 aa) fasta scores: E(): 3.5e-42, 42.21% id in 379 aa.
 
   
 0.676
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
   
 0.616
DIP1512
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 52.9 kDa protein Rv2897c or MT2965 or MTCY274.28C SW:YS97_MYCTU (Q10818) (503 aa) fasta scores: E(): 8.8e-58, 45.63% id in 515 aa, and to Haemophilus influenzae competence protein ComM or HI1117 SW:COMM_HAEIN (P45049) (509 aa) fasta scores: E(): 3.5e-49, 36.59% id in 511 aa.
       0.614
DIP1513
Similar to Streptomyces coelicolor hypothetical protein SC2E1.19 SW:YE19_STRCO (O69890) (130 aa) fasta scores: E(): 2.6e-05, 32.54% id in 126 aa; Belongs to the UPF0102 family.
       0.614
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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