STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1514Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.2 kDa protein Rv2901c or MT2969 or MTCY274.32c SW:YT01_MYCTU (Q10822) (101 aa) fasta scores: E(): 3.7e-31, 70.29% id in 101 aa, and to Streptomyces coelicolor hypothetical 12.3 kDa protein SC2E1.18 TR:O69889 (EMBL:AL023797) (102 aa) fasta scores: E(): 2.9e-27, 67% id in 100 aa. (101 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.831
DIP1516
Putative signal peptidase; Similar to Mycobacterium tuberculosis probable signal peptidase I LepB or Rv2903c or MT2971 or MTCY274.34C SW:LEP_MYCTU (Q10789) (294 aa) fasta scores: E(): 3.3e-40, 44.18% id in 258 aa, and to Bacillus licheniformis signal peptidase I Sip SW:LEP_BACLI (P42668) (186 aa) fasta scores: E(): 5.7e-08, 30.56% id in 229 aa; Belongs to the peptidase S26 family.
       0.806
whiB-3
Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.771
whiB-2
Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.768
secG
Protein transport/translocation membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.758
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
  
     0.753
DIP1511
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 40.1 kDa protein Rv2896c or MT2964 or MTCY274.27C SW:YS96_MYCTU (Q10817) (389 aa) fasta scores: E(): 3.5e-42, 42.21% id in 379 aa.
       0.715
DIP1512
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 52.9 kDa protein Rv2897c or MT2965 or MTCY274.28C SW:YS97_MYCTU (Q10818) (503 aa) fasta scores: E(): 8.8e-58, 45.63% id in 515 aa, and to Haemophilus influenzae competence protein ComM or HI1117 SW:COMM_HAEIN (P45049) (509 aa) fasta scores: E(): 3.5e-49, 36.59% id in 511 aa.
       0.715
DIP1513
Similar to Streptomyces coelicolor hypothetical protein SC2E1.19 SW:YE19_STRCO (O69890) (130 aa) fasta scores: E(): 2.6e-05, 32.54% id in 126 aa; Belongs to the UPF0102 family.
       0.715
whiB
Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.711
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.