Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1520Putative membrane protein; No significant database matches. (769 aa)    
Predicted Functional Partners:
hmuT
Iron-related transport system receptor precursor protein; Identical to previously sequenced Corynebacterium diphtheriae HmuT precursor TR:Q9XD89 (EMBL:AF109162) (353 aa) fasta scores: E(): 3.9e-123, 98.86% id in 353 aa, and highly similar to Corynebacterium ulcerans hemin receptor precursor HmuT TR:Q9EZ57 (EMBL:AF304009) (351 aa) fasta scores: E(): 2.6e-99, 79.83% id in 352 aa.
 
  
 0.881
DIP1519
Putative membrane protein; Similar to Corynebacterium diphtheriae secreted protein precursor TR:Q9XD85 (EMBL:AF109162) (339 aa) fasta scores: E(): 2.7e-34, 42.4% id in 250 aa.
     
 0.774
DIP0523
Putative membrane protein; No significant database matches.
      
 0.604
DIP0624
Putative membrane protein; No significant database matches.
  
  
 0.593
DIP0582
Putative iron transport system binding (secreted) protein; Similar to Escherichia coli iron FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.6e-12, 28.57% id in 287 aa.
   
  
 0.582
DIP1059
Similar to Streptomyces coelicolor putative iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein fepC b0588 SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 1.1e-41, 49.61% id in 262 aa.
   
  
 0.545
DIP0629
Membrane protein; Almost identical to previously sequenced Corynebacterium diphtheriae secreted protein precursor TR:Q9XD85 (EMBL:AF109162) (339 aa) fasta scores: E(): 2.9e-99, 89.21% id in 306 aa.
      
 0.541
DIP1521
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.475
hmuV
Iron-related transport system ATP-binding protein; Almost identical to the previously sequenced Corynebacterium diphtheriae HmuV TR:Q9XD87 (EMBL:AF109162) (277 aa) fasta scores: E(): 3.2e-88, 97.83% id in 277 aa, and to Escherichia coli iron (III) dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 1.2e-23, 41.94% id in 236 aa.
 
    0.473
DIP0625
Putative membrane protein; Similar to the C-terminal region of Corynebacterium ulcerans HtaA TR:Q9EZ58 (EMBL:AF304009) (410 aa) fasta scores: E(): 4.9e-58, 54.14% id in 410 aa, and to Streptomyces coelicolor hypothetical 48.2 kDa protein SCC75A.17c TR:Q9RKQ7 (EMBL:AL133220) (477 aa) fasta scores: E(): 4.9e-06, 26.25% id in 579 aa.
  
   
0.460
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (18%) [HD]