Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1528Similar to Streptomyces coelicolor putative transcriptional accessory protein SC5F2A.26c TR:Q9X7P9 (EMBL:AL049587) (780 aa) fasta scores: E(): 8.5e-161, 59.94% id in 774 aa, and to Escherichia coli protein YhgF or B3407 SW:YHGF_ECOLI (P46837) (773 aa) fasta scores: E(): 7.3e-153, 57.44% id in 766 aa. (758 aa)    
Predicted Functional Partners:
DIP1529
Hypothetical protein; No significant database matches.
       0.785
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.785
rimM
Putative 16s rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.785
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.755
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.749
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.734
DIP1177
Conserved hypothetical protein; C-terminal region similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1730 SWALL:AAK45999 (EMBL:AE007035) (250 aa) fasta scores: E(): 4e-32, 47.73% id in 243 aa, and to Streptomyces coelicolor hypothetical 22.8 kDa protein SCI51.30c SWALL:Q9S210 (EMBL:AL109848) (210 aa) fasta scores: E(): 3.1e-24, 49.17% id in 181 aa.
    
  0.712
DIP2341
Putative integral membrane transport protein; Similar to Escherichia coli O157:H7 putative transporter ECS3800 SWALL:BAB37223 (EMBL:AP002563) (192 aa) fasta scores: E(): 6e-15, 30.16% id in 179 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
    
  0.712
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.625
rpsP
Similar to Mycobacterium leprae 30S ribosomal protein S16 RpsP or ML1618 or MLCB250.32 SW:RS16_MYCLE (O33014) (160 aa) fasta scores: E(): 8.3e-32, 70.39% id in 152 aa, and to Thermus aquaticus 30S ribosomal protein S16 RpsP or Rps16 SW:RS16_THETH (P80379) (88 aa) fasta scores: E(): 6.1e-11, 52.27% id in 88 aa.
       0.620
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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