Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP1539Hypothetical protein; No significant database matches. High content in alanine, leucine and valine amino acid residues Low G+C content (52.14%). (1186 aa)    
Predicted Functional Partners:
smc
Putative chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.667
ftsY
Putative low affinity ammonium uptake protein (pseudogene); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.643
acyP
Similar to Mycobacterium tuberculosis putative acylphosphatase Rv2922.1c or MT2991 or MTCY338.11bc SW:ACYP_MYCTU (P56543) (93 aa) fasta scores: E(): 1.3e-14, 52.08% id in 96 aa, and to Escherichia coli putative acylphosphatase YccX or B0968 or Z1320 or ECS1052 SW:ACYP_ECOLI (P75877) (92 aa) fasta scores: E(): 1.2e-07, 43.82% id in 89 aa.
       0.637
DIP1542
Similar to Staphylococcus aureus (strain N315) amino acid carrier protein AlsT or SA1190 or SAV1356 TR:BAB57518 (EMBL:AP003133) (486 aa) fasta scores: E(): 5.8e-84, 48.83% id in 473 aa, and to Bacillus subtilis amino acid carrier protein AlsT SW:ALST_BACSU (Q45068) (465 aa) fasta scores: E(): 1.3e-73, 46.18% id in 472 aa.
       0.637
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
       0.541
DIP1545
Conserved hypothetical protein; Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical 22.4 kDa protein Rrv2926c or MT2996 or MTCY338.15c SW:YT26_MYCTU (Q10972) (207 aa) fasta scores: E(): 9.5e-13, 30.46% id in 174 aa.
       0.538
mutM
Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.524
DIP1546
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2927c or MT2997 or MTCY338.16c SW:YT27_MYCTU (Q10973) (245 aa) fasta scores: E(): 9e-21, 47.89% id in 238 aa.
       0.449
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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