STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1542Similar to Staphylococcus aureus (strain N315) amino acid carrier protein AlsT or SA1190 or SAV1356 TR:BAB57518 (EMBL:AP003133) (486 aa) fasta scores: E(): 5.8e-84, 48.83% id in 473 aa, and to Bacillus subtilis amino acid carrier protein AlsT SW:ALST_BACSU (Q45068) (465 aa) fasta scores: E(): 1.3e-73, 46.18% id in 472 aa. (495 aa)    
Predicted Functional Partners:
acyP
Similar to Mycobacterium tuberculosis putative acylphosphatase Rv2922.1c or MT2991 or MTCY338.11bc SW:ACYP_MYCTU (P56543) (93 aa) fasta scores: E(): 1.3e-14, 52.08% id in 96 aa, and to Escherichia coli putative acylphosphatase YccX or B0968 or Z1320 or ECS1052 SW:ACYP_ECOLI (P75877) (92 aa) fasta scores: E(): 1.2e-07, 43.82% id in 89 aa.
       0.842
smc
Putative chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.796
mutM
Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.707
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
       0.689
DIP1545
Conserved hypothetical protein; Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical 22.4 kDa protein Rrv2926c or MT2996 or MTCY338.15c SW:YT26_MYCTU (Q10972) (207 aa) fasta scores: E(): 9.5e-13, 30.46% id in 174 aa.
       0.689
DIP1539
Hypothetical protein; No significant database matches. High content in alanine, leucine and valine amino acid residues Low G+C content (52.14%).
       0.655
DIP1546
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2927c or MT2997 or MTCY338.16c SW:YT27_MYCTU (Q10973) (245 aa) fasta scores: E(): 9e-21, 47.89% id in 238 aa.
       0.638
ftsY
Putative low affinity ammonium uptake protein (pseudogene); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.553
gdh
Similar to Corynebacterium glutamicum NADP-specific glutamate dehydrogenase Gdh SW:DHE4_CORGL (P31026) (447 aa) fasta scores: E(): 6.8e-138, 77.84% id in 465 aa, and to Escherichia coli NADP-specific glutamate dehydrogenase GdhA or B1761 SW:DHE4_ECOLI (P00370) (447 aa) fasta scores: E(): 3.6e-97, 59.55% id in 445 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
       0.521
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.