Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
DIP1545Conserved hypothetical protein; Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical 22.4 kDa protein Rrv2926c or MT2996 or MTCY338.15c SW:YT26_MYCTU (Q10972) (207 aa) fasta scores: E(): 9.5e-13, 30.46% id in 174 aa. (176 aa)    
Predicted Functional Partners:
rpmF
Similar to Mycobacterium leprae 50S ribosomal protein L32 RpmF or ML0173 SW:RL32_MYCLE (Q9CD69) (57 aa) fasta scores: E(): 4e-11, 57.14% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.917
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
  
 0.917
DIP1546
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2927c or MT2997 or MTCY338.16c SW:YT27_MYCTU (Q10973) (245 aa) fasta scores: E(): 9e-21, 47.89% id in 238 aa.
     
 0.879
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.857
mutM
Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.824
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.793
rpsP
Similar to Mycobacterium leprae 30S ribosomal protein S16 RpsP or ML1618 or MLCB250.32 SW:RS16_MYCLE (O33014) (160 aa) fasta scores: E(): 8.3e-32, 70.39% id in 152 aa, and to Thermus aquaticus 30S ribosomal protein S16 RpsP or Rps16 SW:RS16_THETH (P80379) (88 aa) fasta scores: E(): 6.1e-11, 52.27% id in 88 aa.
  
    0.782
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
    0.780
rpsB
30S ribosomal protein S2; Similar to Mycobacterium tuberculosis 30S ribosomal protein S2 RpsB or Rv2890c or MT2958 or MTCY274.21c SW:RS2_MYCTU (Q10796) (287 aa) fasta scores: E(): 1.4e-68, 70.94% id in 265 aa, and to Escherichia coli 30S ribosomal protein S2 RpsB or B0169 or Z0180 or ECS0171 SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 2.8e-40, 50.22% id in 225 aa; Belongs to the universal ribosomal protein uS2 family.
  
    0.779
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
    0.779
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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