STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (283 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.947
lspA
Putative lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.938
trpB2
Tryptophan synthase beta chain TrpB2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.871
lnt
Putative transferase/membrane protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
 
   
 0.851
trpC2
Similar to Mycobacterium tuberculosis indole-3-glycerol phosphate synthase TrpC or Rv1611 or MT1646 or MTCY01B2.03 SW:TRPC_MYCTU (O06129) (272 aa) fasta scores: E(): 1.4e-52, 55.59% id in 268 aa, and to Streptomyces coelicolor indole-3-glycerol phosphate synthase 1 TrpC1 or TrpC or SC4G6.08c SW:TRC1_STRCO (O68814) (269 aa) fasta scores: E(): 1.1e-44, 48.28% id in 263 aa.
  
    0.844
trpB1
Tryptophan synthase beta chain TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.826
DIP2196
Conserved putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv3806c or MTV026.11c TR:O53583 (EMBL:AL022076) (302 aa) fasta scores: E(): 1e-67, 59.6% id in 302 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.12 TR:Q9KZA2 (EMBL:AL353872) (322 aa) fasta scores: E(): 1.7e-49, 44.51% id in 310 aa; Belongs to the UbiA prenyltransferase family.
  
    0.679
DIP1695
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 28.7 kDa protein SC4A7.08 TR:Q9RDQ4 (EMBL:AL133423) (273 aa) fasta scores: E(): 1.3e-49, 50.19% id in 259 aa.
  
    0.655
pyk
Pyruvate kinase; Similar to Corynebacterium glutamicum pyruvate kinase Pyk SW:KPYK_CORGL (Q46078) (475 aa) fasta scores: E(): 1.3e-146, 83.36% id in 469 aa, and to Bacillus psychrophilus pyruvate kinase Pyk SW:KPYK_BACPY (P51182) (586 aa) fasta scores: E(): 6.9e-64, 41.45% id in 480 aa.
       0.630
DIP1556
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1645 TR:AAK45914 (EMBL:AE007029) (235 aa) fasta scores: E(): 1e-08, 28.64% id in 206 aa.
       0.599
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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