STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1563Putative membrane protein; No significant database matches. (71 aa)    
Predicted Functional Partners:
hisB
Similar to Corynebacterium glutamicum imidazoleglycerol-phosphate dehydrogenase HisB TR:Q9KJU3 (EMBL:AF160479) (205 aa) fasta scores: E(): 2e-49, 66.33% id in 199 aa, and to Streptomyces coelicolor imidazoleglycerol-phosphate dehydratase HisB or SC4G6.21c SW:HIS7_STRCO (P16247) (197 aa) fasta scores: E(): 1.1e-37, 53.03% id in 198 aa.
       0.773
hisC
Similar to Corynebacterium glutamicum histidinol-phosphate aminotransferase HisC TR:Q9KJU4 (EMBL:AF160478) (366 aa) fasta scores: E(): 1.5e-99, 72.17% id in 363 aa, and to Streptomyces coelicolor histidinol-phosphate aminotransferase HisC or SC4G6.22c SW:HIS8_STRCO (P16246) (369 aa) fasta scores: E(): 3e-79, 57.85% id in 363 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.554
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.474
DIP1562
Similar to Streptomyces coelicolor putative transmembrane transport protein SC5G9.26c TR:Q9RL01 (EMBL:AL117385) (420 aa) fasta scores: E(): 8e-11, 28.37% id in 437 aa, and to Streptomyces lipmanii puromycin resistance protein Pur8 SW:PUR8_STRLP (P42670) (503 aa) fasta scores: E(): 2.4e-08, 24.39% id in 455 aa.
       0.463
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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