STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1567Hypothetical protein; No significant database matches. (351 aa)    
Predicted Functional Partners:
DIP1568
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.648
DIP1569
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.623
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.588
hisC
Similar to Corynebacterium glutamicum histidinol-phosphate aminotransferase HisC TR:Q9KJU4 (EMBL:AF160478) (366 aa) fasta scores: E(): 1.5e-99, 72.17% id in 363 aa, and to Streptomyces coelicolor histidinol-phosphate aminotransferase HisC or SC4G6.22c SW:HIS8_STRCO (P16246) (369 aa) fasta scores: E(): 3e-79, 57.85% id in 363 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.557
hisB
Similar to Corynebacterium glutamicum imidazoleglycerol-phosphate dehydrogenase HisB TR:Q9KJU3 (EMBL:AF160479) (205 aa) fasta scores: E(): 2e-49, 66.33% id in 199 aa, and to Streptomyces coelicolor imidazoleglycerol-phosphate dehydratase HisB or SC4G6.21c SW:HIS7_STRCO (P16247) (197 aa) fasta scores: E(): 1.1e-37, 53.03% id in 198 aa.
       0.513
DIP1562
Similar to Streptomyces coelicolor putative transmembrane transport protein SC5G9.26c TR:Q9RL01 (EMBL:AL117385) (420 aa) fasta scores: E(): 8e-11, 28.37% id in 437 aa, and to Streptomyces lipmanii puromycin resistance protein Pur8 SW:PUR8_STRLP (P42670) (503 aa) fasta scores: E(): 2.4e-08, 24.39% id in 455 aa.
       0.471
hisH
Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.458
impA
Similar to Corynebacterium glutamicum inositol monophosphate phosphatase ImpA TR:O52736 (EMBL:AF045998) (259 aa) fasta scores: E(): 3.2e-42, 50.42% id in 236 aa, and to Mycobacterium smegmatis inositol monophosphate phosphatase ImpA TR:O51845 (EMBL:AF005905) (276 aa) fasta scores: E(): 8e-34, 42.35% id in 255 aa.
       0.446
hisA
Similar to Streptomyces coelicolor phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA or SC4G6.19c SW:HIS4_STRCO (P16250) (240 aa) fasta scores: E(): 2.2e-52, 61.6% id in 237 aa, and to Corynebacterium glutamicum phosphoribosylformimino-5-amino-1-phosphoribosyl-4- imidazolecarboxamide isomerase HisA TR:O68602 (EMBL:AF051846) (245 aa) fasta scores: E(): 8.3e-70, 77.68% id in 242 aa.
       0.446
hisF
Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.440
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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