Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1576Putative RNA-binding heat shock protein; Similar to Rhizobium loti MLR3853 protein TR:Q98FB3 (EMBL:AP003002) (131 aa) fasta scores: E(): 2.9e-09, 42.01% id in 119 aa, and to Escherichia coli heat shock protein 15 HslR or B3400 or Z4754 or ECS4242 SW:HSLR_ECOLI (P45802) (133 aa) fasta scores: E(): 2.7e-06, 32.54% id in 126 aa. (125 aa)    
Predicted Functional Partners:
DIP1577
Putative secreted protein; No significant database matches.
  
  
 0.986
DIP1578
Similar to Bacillus subtilis hypothetical 24.8 kDa protein in degS-tagO intergenic region YvyE or YvhK SW:YVYE_BACSU (P32437) (217 aa) fasta scores: E(): 1.3e-24, 37.5% id in 208 aa.
     
 0.931
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.829
rplQ
Similar to Mycobacterium leprae 50S ribosomal protein L17 RplQ or ML1956 or MLCB1222.26c SW:RL17_MYCLE (Q9X797) (170 aa) fasta scores: E(): 3.1e-26, 58.86% id in 158 aa.
   
 
 0.786
rpmB2
Similar to Mycobacterium tuberculosis 50S ribosomal protein L28-2 RpmB2 or Rv2058c or MT2118 or MTCY63A.02 SW:R28B_MYCTU (O86357) (78 aa) fasta scores: E(): 7.7e-22, 70.51% id in 78 aa; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.781
rpmH
50S ribosomal protein L34; Similar to Mycobacterium paratuberculosis 50S ribosomal protein L34 RpmH SW:RL34_MYCPA (Q9L7L8) (47 aa) fasta scores: E(): 2.9e-15, 80.85% id in 47 aa, to Streptomyces bikiniensis 50S ribosomal protein L34 RpmH SW:RL34_STRBI (P25820) (45 aa) fasta scores: E(): 2.2e-13, 81.39% id in 43 aa, and to Escherichia coli 50S ribosomal protein L34 Rpmh or SsaF or RimA or B3703 or Z5194 or ECS4638 or STM3839 SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 1.1e-07, 59.52% id in 42 aa; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.777
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.770
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.769
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
   0.766
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
   0.766
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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