STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1578Similar to Bacillus subtilis hypothetical 24.8 kDa protein in degS-tagO intergenic region YvyE or YvhK SW:YVYE_BACSU (P32437) (217 aa) fasta scores: E(): 1.3e-24, 37.5% id in 208 aa. (213 aa)    
Predicted Functional Partners:
DIP1576
Putative RNA-binding heat shock protein; Similar to Rhizobium loti MLR3853 protein TR:Q98FB3 (EMBL:AP003002) (131 aa) fasta scores: E(): 2.9e-09, 42.01% id in 119 aa, and to Escherichia coli heat shock protein 15 HslR or B3400 or Z4754 or ECS4242 SW:HSLR_ECOLI (P45802) (133 aa) fasta scores: E(): 2.7e-06, 32.54% id in 126 aa.
     
 0.931
DIP1577
Putative secreted protein; No significant database matches.
     
 0.931
dnaE
Similar to Streptomyces coelicolor DNA polymerase III alpha subunit DnaE or SC4G6.33c SW:DP3A_STRCO (Q9Z618) (1179 aa) fasta scores: E(): 0, 53.84% id in 1185 aa, and to Escherichia coli DNA polymerase III alpha subunit DnaE or PolC or B0184 SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 6.2e-94, 35.39% id in 1198 aa.
     
 0.805
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.791
DIP1581
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD20.10c TR:Q9F2W9 (EMBL:AL392148) (362 aa) fasta scores: E(): 2.4e-45, 45.54% id in 292 aa.
  
    0.494
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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