STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1581Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD20.10c TR:Q9F2W9 (EMBL:AL392148) (362 aa) fasta scores: E(): 2.4e-45, 45.54% id in 292 aa. (299 aa)    
Predicted Functional Partners:
DIP1054
Similar to Mycobacterium leprae hypothetical 16.5 kDa protein ML1147 or u471B SW:YD12_MYCLE (P53432) (147 aa) fasta scores: E(): 4.8e-12, 31.65% id in 139 aa, and to Mycobacterium tuberculosis hypothetical 16.6 kDa protein Rv1312 MT1352 or MTCY373.32 SW:YD12_MYCTU (Q10620) (147 aa) fasta scores: E(): 1.6e-11, 32.37% id in 139 aa, and to Streptomyces coelicolor putative secreted/membrane protein 2sc6g5.19 TR:Q9K4D3 (EMBL:AL359152) (151 aa) fasta scores: E(): 1.1e-05, 27.97% id in 143 aa.
      
 0.837
dnaE
Similar to Streptomyces coelicolor DNA polymerase III alpha subunit DnaE or SC4G6.33c SW:DP3A_STRCO (Q9Z618) (1179 aa) fasta scores: E(): 0, 53.84% id in 1185 aa, and to Escherichia coli DNA polymerase III alpha subunit DnaE or PolC or B0184 SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 6.2e-94, 35.39% id in 1198 aa.
     
 0.723
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.543
DIP1578
Similar to Bacillus subtilis hypothetical 24.8 kDa protein in degS-tagO intergenic region YvyE or YvhK SW:YVYE_BACSU (P32437) (217 aa) fasta scores: E(): 1.3e-24, 37.5% id in 208 aa.
  
    0.498
DIP0589
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD10.06 TR:Q9K3X0 (EMBL:AL359988) (295 aa) fasta scores: E(): 6.6e-36, 43.82% id in 267 aa.
      
 0.487
DIP1576
Putative RNA-binding heat shock protein; Similar to Rhizobium loti MLR3853 protein TR:Q98FB3 (EMBL:AP003002) (131 aa) fasta scores: E(): 2.9e-09, 42.01% id in 119 aa, and to Escherichia coli heat shock protein 15 HslR or B3400 or Z4754 or ECS4242 SW:HSLR_ECOLI (P45802) (133 aa) fasta scores: E(): 2.7e-06, 32.54% id in 126 aa.
       0.450
DIP1577
Putative secreted protein; No significant database matches.
       0.450
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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