STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ag84Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273). (333 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.966
crgA
Putative membrane protein; Involved in cell division; Belongs to the CrgA family.
  
   
 0.924
pknB
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa.
  
 
 0.922
DIP1596
Putative cell division protein precursor; Essential cell division protein.
     
 0.911
pknA
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa.
   
 
 0.909
ftsI
Putative penicillin-binding (cell division related) protein; Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa.
     
 0.907
sepF
Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.852
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
     
 0.830
DIP2294
Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa.
   
 
 0.824
DIP1591
Putative membrane protein; Similar to Streptomyces coelicolor hypothetical 10.7 kDa protein SC4A10.11c TR:Q9S2X3 (EMBL:AL109663) (94 aa) fasta scores: E(): 2.6e-09, 34.78% id in 92 aa, and to Mycobacterium leprae possible membrane protein ML0921 TR:Q9CCE0 (EMBL:AL583920) (96 aa) fasta scores: E(): 6.7e-09, 41.57% id in 89 aa.
 
  
 0.732
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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