STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (149 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.995
DIP1591
Putative membrane protein; Similar to Streptomyces coelicolor hypothetical 10.7 kDa protein SC4A10.11c TR:Q9S2X3 (EMBL:AL109663) (94 aa) fasta scores: E(): 2.6e-09, 34.78% id in 92 aa, and to Mycobacterium leprae possible membrane protein ML0921 TR:Q9CCE0 (EMBL:AL583920) (96 aa) fasta scores: E(): 6.7e-09, 41.57% id in 89 aa.
  
  
 0.961
DIP1596
Putative cell division protein precursor; Essential cell division protein.
  
  
 0.912
ag84
Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273).
  
  
 0.852
DIP1745
Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.851
DIP1599
Putative cell division protein; Similar to Corynebacterium glutamicum FtsW protein TR:Q9L4H4 (EMBL:AJ242646) (490 aa) fasta scores: E(): 9.6e-78, 48.85% id in 481 aa, and to Escherichia coli cell division protein FtsW or B0089 or Z0099 or ECS0093 SW:FTSW_ECOLI (P16457) (414 aa) fasta scores: E(): 1e-21, 32.53% id in 375 aa; Belongs to the SEDS family.
     
 0.805
DIP1594
Conserved hypothetical protein; Similar to Corynebacterium glutamicum hypothetical 26.0 kDa protein in FtsZ 3'region SW:YFTZ_CORGL (P94338) (246 aa) fasta scores: E(): 6.5e-66, 68.72% id in 243 aa, and to Streptomyces griseus hypothetical 25.3 kDa protein in FtsZ 3'region SW:YFTZ_STRGR (P45496) (246 aa) fasta scores: E(): 7.4e-41, 50% id in 228 aa; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
 0.780
DIP1592
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.762
ftsI
Putative penicillin-binding (cell division related) protein; Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa.
     
 0.752
murG
UDP-N-acetylglucosamine-N-acetylmuramyl (pentapeptide); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
     
 0.737
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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