STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1612Similar to Mycobacterium aurum geranylgeranyl pyrophosphate synthase GgpP TR:Q9K567 (EMBL:AJ133724) (371 aa) fasta scores: E(): 1.5e-36, 39.09% id in 353 aa, and to Sulfolobus acidocaldarius geranylgeranyl pyrophosphate synthetase Gds SW:GGPP_SULAC (P39464) (330 aa) fasta scores: E(): 3.1e-11, 28.49% id in 358 aa. (374 aa)    
Predicted Functional Partners:
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 0.992
uppS2
Putative undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.974
uppS1
Putative undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.973
lytB
Putative penicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.935
DIP0429
Similar to Mycobacterium leprae polyprenyl diphosphate synthase component ML2277 TR:Q9CBA5 (EMBL:AL583925) (330 aa) fasta scores: E(): 1.6e-57, 51.69% id in 325 aa, and to Bacillus stearothermophilus heptaprenyl diphosphate synthase component II HepT or HepS-2 SW:HEP2_BACST (P55785) (320 aa) fasta scores: E(): 9.6e-33, 38.99% id in 318 aa.
  
  
 
0.925
DIP1870
Putative phytoene synthase; Similar to Agrobacterium aurantiacum phytoene synthase CrtB SW:CRTB_AGRAU (P54975) (301 aa) fasta scores: E(): 6.8e-09, 29.57% id in 284 aa, and to Corynebacterium glutamicum phytoene synthase CrtB TR:AAK64298 (EMBL:AF159510) (304 aa) fasta scores: E(): 1.1e-51, 51.22% id in 285 aa.
 
 
 0.832
DIP1613
Putative membrane protein; Similar to Mycobacterium tuberculosis putative membrane protein Rv2174 or MTV021.07 TR:O53508 (EMBL:AL021957) (516 aa) fasta scores: E(): 2.2e-56, 34.69% id in 464 aa.
  
 
 0.810
DIP1871
Similar to Neurospora crassa phytoene dehydrogenase Al-1 SW:CRTI_NEUCR (P21334) (595 aa) fasta scores: E(): 1.6e-33, 29.77% id in 524 aa, and to Corynebacterium glutamicum phytoene desaturase CrtI TR:AAK64299 (EMBL:AF159510) (549 aa) fasta scores: E(): 5.6e-107, 54.59% id in 511 aa.
  
  
 0.751
DIP1611
Similar to Streptomyces lividans 5,10-methylenetetrahydrofolate reductase MetF SW:METF_STRLI (O54235) (307 aa) fasta scores: E(): 4.1e-41, 41.58% id in 303 aa, and to Escherichia coli 5,10-methylenetetrahydrofolate reductase MetF or B3941 SW:METF_ECOLI (P00394) (296 aa) fasta scores: E(): 9.2e-15, 33.65% id in 309 aa.
   
 
 0.679
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
    0.636
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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