STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glkGlucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa. (317 aa)    
Predicted Functional Partners:
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
 
 0.994
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.973
ppgK
Polyphosphate glucokinase; Similar to Mycobacterium tuberculosis polyphosphate glucokinase PpgK or Rv2702 or MT2776 or MTCY05A6.23 SW:PPGK_MYCTU (Q59568) (265 aa) fasta scores: E(): 1.5e-50, 57.91% id in 240 aa, and to Corynebacterium ammoniagenes polyphosphate glucokinase PpgK TR:Q9AGV8 (EMBL:AF326348) (277 aa) fasta scores: E(): 3.2e-59, 63.85% id in 249 aa.
  
  
 0.963
pgi
Similar to Escherichia coli glucose-6-phosphate isomerase Pgi or B4025 or Z5623 or ECS5008 SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 2e-104, 52.71% id in 552 aa, and to Mycobacterium tuberculosis glucose-6-phosphate isomerase Pgi or Rv0946c or MT0972 or MTCY10D7.28 SW:G6PI_MYCTU (P77895) (553 aa) fasta scores: E(): 2.6e-133, 62.75% id in 545 aa.
  
 
 0.947
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
     
 0.927
DIP1011
Similar to putative aldose 1-epimerases e.g. Escherichia coli O157:H7 putative aldose-1-epimerase ECS4802 TR:BAB38225 (EMBL:AP002567) (300 aa) fasta scores: E(): 3.1e-21, 29.09% id in 299 aa, and to Escherichia coli hypothetical protein YihR or B3879 SW:YIHR_ECOLI (P32139) (308 aa) fasta scores: E(): 7.7e-21, 30.35% id in 280 aa, and to Salmonella typhimurium putative aldose-1-epimerase YihR TR:Q9L7R7 (EMBL:AF220438) (280 aa) fasta scores: E(): 1.1e-13, 29.53% id in 281 aa. Contains weak match to PFAM:PF01263 Aldose 1-epimerase E: 0.089.
    
 0.905
DIP0115
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 39.2 kDa protein SCH24.21c TR:Q9X8T5 (EMBL:AL049826) (360 aa) fasta scores: E(): 5e-111, 79.49% id in 356 aa.
     
  0.900
DIP2344
Conserved hypothetical protein; Weakly similar to many eg. Escherichia coli unknown protein from 2d-page YeaD or B1780 SWALL:UP08_ECOLI (SWALL:P39173) (294 aa) fasta scores: E(): 0.00013, 28.74% id in 247 aa.
     
  0.900
pgl
Putative phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
     
 0.870
DIP0892
Similar to Streptomyces coelicolor putative glyceraldehyde-3-phosphate dehydrogenase SC4G1.06c TR:Q9FC43 (EMBL:AL391039) (481 aa) fasta scores: E(): 1.8e-99, 54.44% id in 472 aa and C-terminal region similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 GapA or Gap SW:G3P1_BACSU (P09124) (334 aa) fasta scores: E(): 6.7e-40, 41.39% id in 343 aa.
      
 0.869
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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