STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1632Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SC5F7.32 TR:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 4.8e-10, 30.45% id in 220 aa. (224 aa)    
Predicted Functional Partners:
cobU
Putative cobinamide kinase; Similar to Mycobacterium tuberculosis cobinamide kinase CobU or Rv0254c or MTV034.20 TR:O53676 (EMBL:AL021929) (174 aa) fasta scores: E(): 6.7e-21, 44.38% id in 178 aa, and to Escherichia coli, and bifunctional cobalamin biosynthesis protein CobU [includes: cobinamide kinase; cobinamide phosphate guanylyltransferase] or B1993 or Z3153 or ECS2788 SW:COBU_ECOLI (P46886) (181 aa) fasta scores: E(): 1.8e-13, 35.48% id in 186 aa.
       0.842
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
       0.742
cobS
Putative cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
       0.742
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.717
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.715
DIP0729
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 49.4 kDa protein Rv3195 or MTV014.39 TR:O53341 (EMBL:AL021646) (472 aa) fasta scores: E(): 5.1e-65, 45.37% id in 432 aa.
  
     0.687
DIP0413
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 57.1 kDa protein Rv0528 or MTCY25D10.07 TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 3.9e-103, 49.43% id in 532 aa.
  
     0.666
DIP1631
Conserved hypothetical protein; Similar to Corynebacterium glutamicum ORF1 TR:Q9LCB6 (EMBL:AB029550) (114 aa) fasta scores: E(): 3.2e-36, 84.21% id in 114 aa, and to Escherichia coli hypothetical protein YadR or B0156 or Z0167 or ECS0160 SW:YADR_ECOLI (P37026) (114 aa) fasta scores: E(): 7.2e-15, 44.66% id in 103 aa; Belongs to the HesB/IscA family.
       0.656
DIP1642
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rvv2219 precursor or MT2276 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 2.4e-36, 42.8% id in 250 aa.
 
     0.648
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
  
     0.621
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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