STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1678Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 39.8 kDa protein ML1637 or MLCB1243.38 TR:O69483 (EMBL:AL023635) (371 aa) fasta scores: E(): 1.8e-73, 54.61% id in 379 aa. (377 aa)    
Predicted Functional Partners:
DIP1679
Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2229c or MT2288 or MTCY427.10c SW:YM29_MYCTU (Q10513) (245 aa) fasta scores: E(): 1.9e-06, 23.75% id in 240 aa.
  
  
 0.971
cobS
Putative cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.933
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.927
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.830
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
 
 0.820
ssb1
Similar to Mycobacterium tuberculosis single-strand binding protein Ssb or Rv0054 or MT0060 or MTCY21D4.17 SWALL:SSB_MYCTU (SWALL:P71711) (164 aa) fasta scores: E(): 2e-27, 60.2% id in 191 aa. Note: Also similar to DIP2216 (171 aa) fasta scores: E(): 2.6e-44, 68.750% identity in 176 aa overlap.
 
 
 0.782
DIP1680
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 40.3 kDa protein ML1639 or MLCB1243.36 TR:O69481 (EMBL:AL023635) (385 aa) fasta scores: E(): 4.3e-74, 54.27% id in 374 aa; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
    0.764
DIP1804
Similar to Mycobacterium tuberculosis single-strand binding protein Ssb SW:SSB_MYCTU (P71711) (164 aa) fasta scores: E(): 0.00073, 29.11% id in 158 aa, and to Mycobacterium smegmatis single-stranded DNA-binding protein TR:Q9AFI5 (EMBL:AF349434) (165 aa) fasta scores: E(): 0.00024, 27.95% id in 161 aa.
   
 0.750
ssb2
Similar to Mycobacterium tuberculosis single-strand binding protein Ssb or Rv0054 or MT0060 or MTCY21D4.17 SW:SSB_MYCTU (P71711) (164 aa) fasta scores: E(): 7.2e-31, 56.647% id in 173 aa, and to Bacillus subtilis single-strand binding protein Ssb SW:SSB_BACSU (P37455) (172 aa) fasta scores: E(): 3.4e-13, 38.372% id in 172 aa. Note: Also similar to DIP2290 (193 aa) fasta scores: E(): 6.4e-45, 68.750% identity in 176 aa overlap.
   
 0.750
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
   
   0.722
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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