Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1682Similar to Alcaligenes eutrophus phosphoglycolate phosphatase, chromosomal CbbZC SW:GPHC_ALCEU (P40852) (231 aa) fasta scores: E(): 3.5e-08, 30.85% id in 188 aa. (214 aa)    
Predicted Functional Partners:
DIP1683
Similar to Streptomyces coelicolor low molecular weight protein-tyrosine-phosphatase PtpA or SCQ11.04c SW:PTPA_STRCO (P53433) (164 aa) fasta scores: E(): 1.3e-21, 47.43% id in 156 aa, and to Bos taurus low molecular weight phosphotyrosine protein phosphatase Acp1 SW:PPAC_BOVIN (P11064) (157 aa) fasta scores: E(): 9.2e-12, 35.55% id in 135 aa.
     
 0.805
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.756
DIP1681
Similar to Mycobacterium tuberculosis putative aminotransferase Rv2231c or MT2290 or MTCY427.12c SW:YM31_MYCTU (Q10503) (364 aa) fasta scores: E(): 1.7e-50, 45.67% id in 335 aa and to Salmonella typhimurium CobD TR:P97084 (EMBL:U90625) (364 aa) fasta scores: E(): 3.6e-18, 27.76% id in 335 aa.
  
  
 0.732
DIP1684
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 29.8 kDa protein Rv2235 precursor or MT2294 or MTCY427.16 SW:YM35_MYCTU (Q10517) (271 aa) fasta scores: E(): 1.4e-34, 38.54% id in 275 aa.
       0.731
DIP1680
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 40.3 kDa protein ML1639 or MLCB1243.36 TR:O69481 (EMBL:AL023635) (385 aa) fasta scores: E(): 4.3e-74, 54.27% id in 374 aa; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.716
DIP1678
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 39.8 kDa protein ML1637 or MLCB1243.38 TR:O69483 (EMBL:AL023635) (371 aa) fasta scores: E(): 1.8e-73, 54.61% id in 379 aa.
       0.598
DIP1679
Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2229c or MT2288 or MTCY427.10c SW:YM29_MYCTU (Q10513) (245 aa) fasta scores: E(): 1.9e-06, 23.75% id in 240 aa.
       0.598
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.591
DIP2130
Full length similarity to Streptococcus pneumoniae phosphoribosylformylglycinamidine synthase, putative SP0045 TR:AAK74234 (EMBL:AE007322) (1241 aa) fasta scores: E(): 7.8e-167, 47.73% id in 1259 aa. Second two thirds similar to many others e.g. Mycobacterium tuberculosis phosphoribosylformylglycinamidine synthase II PurL or Rv0803 or MT0823 or MTCY07H7A.06c SW:PURL_MYCTU (P54876) (754 aa) fasta scores: E(): 8.3e-22, 26.35% id in 740 aa.
  
  
 0.591
rpe
Similar to Mycobacterium tuberculosis ribulose-phosphate 3-epimerase Rpe or Rv1408 or MT1452 or MTCY21B4.25 SWALL:RPE_MYCTU (SWALL:P71676) (229 aa) fasta scores: E(): 2e-49, 58.63% id in 220 aa, and to Escherichia coli ribulose-phosphate 3-epimerase Rpe or Dod or B3386 or Z4739 or ECS4228 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 1.3e-30, 43.19% id in 213 aa.
  
  
 0.460
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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