STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1703Similar to Mycobacterium smegmatis deoxyguanosinetriphosphate triphosphohydrolase Dgt SW:DGTP_MYCSM (O52199) (428 aa) fasta scores: E(): 4.9e-75, 52.43% id in 410 aa, and to Escherichia coli deoxyguanosinetriphosphate triphosphohydrolase Dgt or B0160 SW:DGTP_ECOLI (P15723) (504 aa) fasta scores: E(): 0.0013, 29.92% id in 274 aa; Belongs to the dGTPase family. Type 2 subfamily. (423 aa)    
Predicted Functional Partners:
DIP1693
Putative N-acetylglucosamine related protein; Similar to Streptomyces coelicolor conserved hypothetical protein SCE20.17c TR:Q9RDA8 (EMBL:AL136058) (259 aa) fasta scores: E(): 4.9e-62, 65.86% id in 249 aa, and to Escherichia coli NagD protein or B0675 or Z0822 or ECS0705 SW:NAGD_ECOLI (P15302) (250 aa) fasta scores: E(): 1e-37, 43.02% id in 251 aa; Belongs to the HAD-like hydrolase superfamily.
   
 
  0.908
ndk
Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.901
deoD
Putative transposase (pseudogene); Possible inverted repeat.
     
  0.900
DIP0465
Conserved hypothetical protein; Similar to C-terminal region of Alcaligenes eutrophus NrdD protein TR:Q9ZER4 (EMBL:AJ012479) (676 aa) fasta scores: E(): 1.4e-167, 71.81% id in 550 aa.
     
  0.900
DIP1704
Putative secreted protein; No significant database matches.
  
    0.841
DIP1705
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 70.0 kDa protein Rv2345 or MTCY98.14 TR:P95241 (EMBL:Z83860) (660 aa) fasta scores: E(): 1.6e-41, 30.4% id in 671 aa.
       0.666
tsaD
Putative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
     
 0.515
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  
  
 0.486
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
 
     0.484
recO
Putative DNA-repair related protein; Involved in DNA repair and RecF pathway recombination.
     
 0.452
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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