STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1711Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein PA3851 TR:Q9HXF5 (EMBL:AE004802) (250 aa) fasta scores: E(): 9.2e-22, 38.29% id in 235 aa, and to Pyrococcus abyssi hypothetical 40.7 kDa protein PAB1273 TR:Q9UY73 (EMBL:AJ248288) (364 aa) fasta scores: E(): 1.3e-12, 28.69% id in 345 aa. (331 aa)    
Predicted Functional Partners:
uppS2
Putative undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
       0.616
recO
Putative DNA-repair related protein; Involved in DNA repair and RecF pathway recombination.
       0.585
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.585
pdxY
Putative pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
       0.498
DIP1716
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 47.2 kDa protein Rv2366c or MT2435 or MTCY27.14 SW:YN66_MYCTU (O05832) (435 aa) fasta scores: E(): 1.1e-67, 53.91% id in 434 aa.
       0.497
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.497
DIP1718
Putative PhoH-like protein; Similar to Mycobacterium tuberculosis PhoH-like protein Rv2368c or MT2437 or MTCY27.12 SW:PHOL_MYCTU (O05830) (352 aa) fasta scores: E(): 2.2e-66, 63.25% id in 313 aa, and to Bacillus subtilis PhoH-like protein PhoH SW:PHOL_BACSU (P46343) (319 aa) fasta scores: E(): 2.9e-52, 52.47% id in 303 aa.
       0.497
DIP1719
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.433
dnaJ2
Chaperone protein 2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
       0.433
DIP1004
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein Rv1249c or MTV006.21c TR:O50464 (EMBL:AL021006) (262 aa) fasta scores: E(): 2.1e-15, 31.57% id in 209 aa.
  
     0.418
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.