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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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eraPutative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (305 aa)    
Predicted Functional Partners:
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.943
recO
Putative DNA-repair related protein; Involved in DNA repair and RecF pathway recombination.
  
  
 0.925
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 
 0.881
uppS2
Putative undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.875
DIP1718
Putative PhoH-like protein; Similar to Mycobacterium tuberculosis PhoH-like protein Rv2368c or MT2437 or MTCY27.12 SW:PHOL_MYCTU (O05830) (352 aa) fasta scores: E(): 2.2e-66, 63.25% id in 313 aa, and to Bacillus subtilis PhoH-like protein PhoH SW:PHOL_BACSU (P46343) (319 aa) fasta scores: E(): 2.9e-52, 52.47% id in 303 aa.
 
  
 0.850
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.835
DIP1716
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 47.2 kDa protein Rv2366c or MT2435 or MTCY27.14 SW:YN66_MYCTU (O05832) (435 aa) fasta scores: E(): 1.1e-67, 53.91% id in 434 aa.
 
    0.785
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
 
  0.782
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 0.779
rpsP
Similar to Mycobacterium leprae 30S ribosomal protein S16 RpsP or ML1618 or MLCB250.32 SW:RS16_MYCLE (O33014) (160 aa) fasta scores: E(): 8.3e-32, 70.39% id in 152 aa, and to Thermus aquaticus 30S ribosomal protein S16 RpsP or Rps16 SW:RS16_THETH (P80379) (88 aa) fasta scores: E(): 6.1e-11, 52.27% id in 88 aa.
    
 0.754
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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